MedTrace Logo

Fungicide Exposure Assessment Among Apple and Peach Farmers in the Argicultural Health Study

NCT00342394 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 75

Last updated 2018-04-05

No results posted yet for this study

Summary

This protocol describes an exposure assessment study of farmers in North Carolina and Iowa who personally apply the fungicides captan, thiophanate-methyl, and benomyl to apple and peach orchards. The exposure assessment will include environmental measurements as well as biological monitoring data. The biomonitoring data will be based on 24-hour urinary metabolites of the three fungicides selected for study. The study is being done in collaboration with the Argicultural Health Study (AHS), a large prospective health study of licensed private (farmer) and commercial applicators, and the spouses of private applicators. The AHS is sponsored by the National Cancer Institute, the National Institute of Environmental Health Sciences and the Environmental Protection Agency. The study described here will be conducted by the National Institute of Occupational Safety and Health.

In summary, the objectives of this study are 1) to measure actual exposures to the target fungicides using both environmental and biological measures of exposure, 2) to identify and quantify major determinants of exposure, 3) to describe within- and between-worker exposure variability, and 4) to evaluate, to the extent possible, agreement between exposure estimates computed using the AHS exposure algorithms and exposure estimates based on actual measurements.

Conditions

  • Pesticides
  • Occupational Exposure

Sponsors & Collaborators

Principal Investigators

  • Michael Alavanja, Ph.D. · National Cancer Institute (NCI)

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2001-11-14
Completion
2013-05-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00342394 on ClinicalTrials.gov