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Study to Improve Scientific Understanding of the Cardiovascular Actions of Cocaine

NCT00338546 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL

Last updated 2019-01-16

No results posted yet for this study

Summary

The purpose of this study is to improve the scientific understanding of the cardiovascular actions of cocaine, in particular the ability of cocaine to increase blood pressure.

Conditions

  • Cocaine Induced Sympathoexciation and Vasoconstriction

Interventions

DRUG

Cocaine hydrochloride

DRUG

Dexmedetomidine

PROCEDURE

Microneurography

PROCEDURE

Laser doppler velocimetry

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • University of Texas Southwestern Medical Center

    lead OTHER

Principal Investigators

  • Ronald G Victor, MD · Univ of Texas Southwestern Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00338546 on ClinicalTrials.gov