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Efficacy of Lansoprazole in Chronic Post Nasal Drip

NCT00335283 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2012-08-21

Study results available
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Summary

The purpose of this study is to determine whether aggressive acid suppression with Lansoprazole is effective in the treatment of post nasal drip, and also assess the predictors of response based on clinical and physiologic parameters.

Conditions

  • Larynx Disease

Interventions

DRUG

Lansoprazole Tablet

40 mg bid x 16 weeks

PROCEDURE

PH and impedence testing

24 hour ph monitoring

PROCEDURE

manometry

done prior to pH probe to measure length of esophagus

DRUG

lansoprazole

40mg bid

DRUG

placebo

one tablet bid

Sponsors & Collaborators

  • TAP Pharmaceutical Products Inc.

    collaborator INDUSTRY

  • Vanderbilt University

    lead OTHER

Principal Investigators

  • Michael F Vaezi, MD PhD MS · Vanderbilt University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-08-31
Primary Completion
2008-12-31
Completion
2008-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00335283 on ClinicalTrials.gov