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A Study of MSI-1256F (Squalamine Lactate) To Treat "Wet" Age-Related Macular Degeneration

NCT00333476 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 140

Last updated 2007-11-28

No results posted yet for this study

Summary

Age-Related Macular Degeneration (AMD) is a degenerative eye disease of the retina that causes a progressive loss of central vision. AMD is the leading cause of legal blindness among adults age 50 or older in the Western world. AMD presents in two different types - "dry" and the more severe "wet" form. Wet AMD is caused by the growth of abnormal blood vessels in the macula. Squalamine lactate is an investigational drug that may prevent the growth of these abnormal blood vessels. This study will test the safety and efficacy of Squalamine in the treatment of AMD.

Conditions

  • Macular Degeneration

Interventions

DRUG

MSI-1256F (Squalamine Lactate)

Sponsors & Collaborators

  • Genaera Corporation

    lead INDUSTRY

Principal Investigators

  • Randy Katz, MD · Florida Eye Microsurgical Institute, Inc.

  • Alexander Eaton, MD · Retina Health Center

  • Thomas Ciulla, MD · Midwest Eye Institute

  • Raymond Sjaarda, MD · Retina Specialists

  • Nelson Sabates, MD · Eye Foundation of Kansas City

  • Charles Garcia, MD · Charles Garcia, MD, P.A.

  • Glenn Stoller, MD · Ophthalmic Consultants of Long Island

  • Phillip Rosenfeld, MD · Bascom Palmer Eye Institute

  • Steven Rose, MD · Retina Associates of Western New York

Study Design

Allocation
RANDOMIZED
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00333476 on ClinicalTrials.gov