Vorinostat in Treating Patients With Progressive Metastatic Prostate Cancer
NCT00330161 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 29
Last updated 2014-05-26
Summary
This phase II trial is studying how well vorinostat works in treating patients with progressive metastatic prostate cancer. Drugs used in chemotherapy, such as vorinostat, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Vorinostat may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Conditions
- Recurrent Prostate Cancer
- Stage IV Prostate Cancer
Interventions
- DRUG
-
vorinostat
Given orally
- OTHER
-
laboratory biomarker analysis
Correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Maha Hussain · University of Michigan
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-03-31
- Primary Completion
- 2009-09-30
- Completion
- 2011-05-31
Countries
- United States
Study Locations
More Related Trials
-
Bortezomib With or Without Hormone Therapy in Treating Patients With Relapsed Prostate Cancer
NCT00103376 ·Status: TERMINATED ·Phase: PHASE2
-
Carboplatin, Everolimus, and Prednisone in Treating Patients With Metastatic Prostate Cancer That Progressed After Docetaxel
NCT01051570 ·Status: COMPLETED ·Phase: PHASE2
-
Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer
NCT01174199 ·Status: TERMINATED ·Phase: PHASE1
-
Paclitaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer
NCT00003614 ·Status: COMPLETED ·Phase: PHASE2
-
Perifosine in Treating Patients With Recurrent Prostate Cancer
NCT00058214 ·Status: TERMINATED ·Phase: PHASE2
-
Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer
NCT05733351 ·Status: TERMINATED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00006114 ·Status: UNKNOWN ·Phase: PHASE2
-
Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
NCT05806515 ·Status: RECRUITING ·Phase: PHASE2
-
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
NCT03678025 ·Status: RECRUITING ·Phase: PHASE3
-
S9916, Combination Therapy in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00004001 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer
NCT00003394 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer
NCT00589472 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer
NCT00003633 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study to Evaluate the Safety and Efficacy of Enzalutamide in Chemotherapy-Naïve, Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer
NCT01663415 ·Status: WITHDRAWN ·Phase: PHASE2
-
Combination Chemotherapy Plus Filgrastim in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00005810 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel in Treating Patients With Stage II or Stage III Prostate Cancer
NCT00005096 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I Dose-escalation Study of Fractionated 177Lu-PSMA-617 for Progressive Metastatic CRPC
NCT03042468 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Hsp90 Inhibitor STA-9090 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
NCT01270880 ·Status: COMPLETED ·Phase: PHASE2
-
Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC
NCT04506567 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of Olaparib and Durvalumab in Prostate Cancer
NCT03810105 ·Status: TERMINATED ·Phase: PHASE2
-
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
NCT05997615 ·Status: RECRUITING ·Phase: PHASE1
-
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
NCT05803941 ·Status: RECRUITING ·Phase: PHASE4
-
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
NCT06632977 ·Status: RECRUITING ·Phase: PHASE2
-
Arsenic Trioxide in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Previous Hormone Therapy
NCT00004149 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Study of PCUR-101 in Combination With Androgen Suppression Therapy in the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
NCT03137758 ·Status: TERMINATED ·Phase: PHASE1