Ceftobiprole in the Treatment of Patients With Community-Acquired Pneumonia
NCT00326287 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 638
Last updated 2012-08-02
Summary
The purpose of this study is to compare the clinical cure rate (ratio of clinically cured patients to the total number of patients) of ceftobiprole medocaril versus a comparator in the treatment of patients with community-acquired pneumonia.
Conditions
Interventions
- DRUG
-
Ceftobiprole medocaril
- DRUG
-
Ceftriaxone with or without Linezolid
Sponsors & Collaborators
-
Basilea Pharmaceutica
lead INDUSTRY
Principal Investigators
-
Johnson & Johnson Pharmaceutical Research & Development, L.L. C. Clinical Trial · Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-06-30
- Primary Completion
- 2007-07-31
- Completion
- 2007-07-31
More Related Trials
-
Effect of Ceftobiprole on Human Intestinal Microflora
NCT00965042 ·Status: COMPLETED ·Phase: PHASE1
-
Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections
NCT03137173 ·Status: COMPLETED ·Phase: PHASE3
-
Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia
NCT00621504 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Penetration of Ceftobiprole Into Soft Tissue Determined by Microdialysis in Healthy Volunteers
NCT01026740 ·Status: COMPLETED ·Phase: PHASE1
-
Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age
NCT05856227 ·Status: COMPLETED ·Phase: PHASE3
-
Cefiderocol vs Best Available Therapy for Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex Infections: A Target Trial Emulation
NCT07226557 ·Status: ACTIVE_NOT_RECRUITING
-
Vancomycin Versus Ceftaroline in Patients With Infections Caused by MRSA That Are Susceptible to Ceftaroline
NCT01724671 ·Status: UNKNOWN
-
Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia
NCT03163446 ·Status: COMPLETED ·Phase: PHASE2
-
Individualized Precision Therapy With Ceftobiprole Guided by PK/PD in Geriatric Populations
NCT07127185 ·Status: NOT_YET_RECRUITING
-
Comparative Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia
NCT00538694 ·Status: COMPLETED ·Phase: PHASE3
-
Ceftobiprole in the Treatment of Pediatric Patients With Pneumonia
NCT03439124 ·Status: COMPLETED ·Phase: PHASE3
-
Open and Exploratory Trial to Investigate the Pharmacokinetic of Ceftobiprole Medocaril in Patients With CSF Device
NCT03317093 ·Status: COMPLETED ·Phase: PHASE2
-
Cefepime vs. Ceftriaxone to Treat Nursing Home-Acquired Pneumonia
NCT00358202 ·Status: COMPLETED ·Phase: PHASE4
-
Optimizing Clinical Use of Polymyxin B
NCT02682355 ·Status: COMPLETED
-
Evaluation of the Tolerance of Ceftaroline and Ceftobiprole in the Management of BJI / PJI
NCT04409769 ·Status: COMPLETED
-
Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens
NCT03032380 ·Status: COMPLETED ·Phase: PHASE3
-
IL-10 Stratifying Tool for Towards Antibiotic Selection for MRSaB
NCT02660346 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008)
NCT02070757 ·Status: COMPLETED ·Phase: PHASE3
-
Open Label Pharmacokinetic in Adult Patients With Ventilator-Associated Pneumonia
NCT00771719 ·Status: TERMINATED ·Phase: PHASE1
-
Rapid Detection of Bacterial Resistance by MALDI-TOF MS and Antibiotic Savings
NCT02860247 ·Status: COMPLETED
-
Evaluation of Ceftaroline Fosamil Versus a Comparator in Adult Subjects With Community-acquired Bacterial Pneumonia (CABP) With Risk for Methicillin-resistant Staphylococcus Aureus
NCT01645735 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens
NCT02714595 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Antibiotic Choice On ReNal Outcomes (ACORN)
NCT05094154 ·Status: COMPLETED ·Phase: PHASE4
-
A Post-Marketing Study to Assess the Efficacy and Safety of Intravenous Polymyxin B and Colistin Methanesulfonate in Patients With Carbapenem-Resistant Gram-Negative Bacterial Infection
NCT06966284 ·Status: RECRUITING
-
Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)
NCT01530763 ·Status: COMPLETED ·Phase: PHASE2/PHASE3