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A Stepwise Strategy Utilizing Buprenorphine and Methadone

NCT00310934 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 96

Last updated 2006-10-24

No results posted yet for this study

Summary

The objective of this study is to compare optimally given methadone maintenance treatment (MMT) for heroin dependence with a novel, sequential strategy, where patients are offered buprenorphine as first line treatment, allowed dose adjustments as needed, and switched to methadone if the maximal dose of buprenorphine is insufficient.

Conditions

  • Heroin Dependence

Interventions

DRUG

methadone

DRUG

buprenorphine / methadone sequence

BEHAVIORAL

Relapse prevention

BEHAVIORAL

Contingency management

Sponsors & Collaborators

  • Swedish National Drug Policy Coordinator

    collaborator UNKNOWN

  • Region Stockholm

    collaborator OTHER_GOV

  • Schering-Plough

    collaborator INDUSTRY

  • Karolinska University Hospital

    lead OTHER

Principal Investigators

  • Markus Heilig, MD PhD · Karolinska Institute, Stockholm

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-08-31
Completion
2006-03-31

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00310934 on ClinicalTrials.gov