AZD2171 in Treating Patients With Recurrent Glioblastoma Multiforme
NCT00305656 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 31
Last updated 2013-08-22
Summary
This phase II trial is studying how well AZD2171 works in treating patients with recurrent glioblastoma multiforme. AZD2171 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor
Conditions
- Adult Giant Cell Glioblastoma
- Adult Glioblastoma
- Adult Gliosarcoma
- Recurrent Adult Brain Tumor
Interventions
- DRUG
-
cediranib maleate
Given orally
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Tracy Batchelor · Massachusetts General Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-01-31
- Primary Completion
- 2012-04-30
Countries
- United States
Study Locations
More Related Trials
-
CT-322 in Treating Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan
NCT00562419 ·Status: UNKNOWN ·Phase: PHASE2
-
Low Dose Radiation Therapy for Glioblastoma Multiforme
NCT01466686 ·Status: COMPLETED ·Phase: PHASE2
-
Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma
NCT00017264 ·Status: COMPLETED ·Phase: PHASE1
-
AZD2171 in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibroma and/or Neurofibroma Near the Spine
NCT00326872 ·Status: TERMINATED ·Phase: PHASE2
-
AZD8055 for Adults With Recurrent Gliomas
NCT01316809 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of MEDI-575 in Subjects With Recurrent Glioblastoma Multiforme
NCT01268566 ·Status: COMPLETED ·Phase: PHASE2
-
ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma
NCT00352313 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Fenretinide in Treating Patients With Recurrent Malignant Glioma
NCT00006080 ·Status: COMPLETED ·Phase: PHASE2
-
Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
NCT00423735 ·Status: COMPLETED ·Phase: PHASE2
-
SU5416 in Treating Patients With Recurrent Astrocytoma or Mixed Glioma That Has Not Responded to Radiation Therapy
NCT00004868 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Motexafin Gadolinium, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
NCT00305864 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma
NCT00005637 ·Status: COMPLETED ·Phase: PHASE1
-
Oxaliplatin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00005856 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Cediranib Maleate With or Without Gefitinib in Treating Patients With Recurrent or Progressive Glioblastoma
NCT01310855 ·Status: TERMINATED ·Phase: PHASE2
-
Safety and Efficacy of TRPP Therapy in Glioblastoma Multiforme
NCT05589961 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Biological Therapy in Treating Patients With Glioblastoma Multiforme
NCT00003185 ·Status: COMPLETED ·Phase: PHASE2
-
Bortezomib in Treating Patients With Recurrent Glioma
NCT00006773 ·Status: TERMINATED ·Phase: PHASE1
-
Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00731731 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Erlotinib in Treating Patients With Recurrent or Progressive Glioblastoma Multiforme
NCT00054496 ·Status: UNKNOWN ·Phase: PHASE2
-
Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
NCT01089101 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma
NCT00070525 ·Status: COMPLETED ·Phase: PHASE2
-
Karenitecin in Treating Patients With Recurrent Malignant Glioma
NCT00014521 ·Status: COMPLETED ·Phase: PHASE1
-
Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma
NCT00979862 ·Status: COMPLETED ·Phase: PHASE1
-
Gefitinib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00014170 ·Status: COMPLETED ·Phase: PHASE2
-
Gefitinib in Treating Patients With Recurrent or Progressive CNS Tumors
NCT00025675 ·Status: COMPLETED ·Phase: PHASE2