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Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Choriocarcinoma

NCT00294177 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2006-02-20

No results posted yet for this study

Summary

Gestational trophoblastic disease comprises a spectrum of diseases with different propensity for local invasion and metastasis, that is, partial and complete hydatidiform mole, choriocarcinoma, and placental site trophoblastic tumor.All trophoblastic tumors produce hCG, and monitoring of therapy is largely based on the determination of hCG in serum. The conformational change of tumor markers during antineoplastic chemotherapy for cancer and its clinical meaning has only been rarely studied. In this study, we will try to understand the conformational change of the tumor marker (hCG) during chemotherapy.

Conditions

  • Trophoblastic Neoplasms
  • Choriocarcinoma

Interventions

DEVICE

atomic force microscopy

DEVICE

dual polarisation interferometry

Sponsors & Collaborators

  • National Science and Technology Council, Taiwan

    collaborator OTHER_GOV

  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Ruey-Jien Chen · Department or Obstetrics and Gynecology, National Taiwan university Hospital

Eligibility

Min Age
0 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-08-31
Completion
2008-07-31

Countries

  • Taiwan

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00294177 on ClinicalTrials.gov