Efficacy and Safety of ABT-874 in Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT00292396 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 180
Last updated 2013-01-18
Summary
The purpose of the study is to assess the safety and efficacy of ABT-874 in the treatment of moderate to severe chronic plaque psoriasis.
Conditions
Interventions
- DRUG
-
Anti IL-12 monoclonal antibody/ABT-874
Please see Arm Description for intervention description and details.
- DRUG
-
12 doses
Sponsors & Collaborators
-
AbbVie (prior sponsor, Abbott)
lead INDUSTRY
Principal Investigators
-
Martin Kaul, MD · AbbVie
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-11-30
- Primary Completion
- 2008-04-30
- Completion
- 2008-04-30
Countries
- United States
- Canada
Study Locations
More Related Trials
-
Efficacy and Safety of Subcutaneous Abatacept in Adults With Active Psoriatic Arthritis
NCT01860976 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Abatacept Versus Placebo in Participants With Psoriatic Arthritis
NCT00534313 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase 3 Study in Participants With Moderate to Severe Psoriasis
NCT01474512 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis
NCT06934226 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study to Assess Usability of Risankizumab Autoinjector Combination Product in Participants With Moderate to Severe Plaque Psoriasis
NCT03875508 ·Status: COMPLETED ·Phase: PHASE3
-
Observational Study of Patients With Moderate to Severe Chronic Plaque Psoriasis
NCT03982394 ·Status: COMPLETED
-
A Study to Assess Safety and Efficacy of Risankizumab Using a New Formulation in Participants With Moderate to Severe Plaque Psoriasis
NCT03875482 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate Effectiveness and Safety in Subjects With Moderate to Severe Psoriasis
NCT02931838 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate ABY-035 in Subjects With Moderate-to-severe Plaque Psoriasis
NCT03591887 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety/Tolerability of Subcutaneous Tildrakizumab (SCH 900222/MK-3222) in Participants With Moderate-to-Severe Chronic Plaque Psoriasis Followed by a Long-term Extension Study (MK-3222-011)
NCT01729754 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of ABY-035
NCT02690142 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of BMS-582949 in Patients With Moderate to Severe Plaque Psoriasis
NCT00399906 ·Status: COMPLETED ·Phase: PHASE2
-
A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT03410992 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase 3 Study in Participants With Moderate to Severe Psoriasis (UNCOVER-2)
NCT01597245 ·Status: COMPLETED ·Phase: PHASE3
-
BI 655066 Versus Placebo & Active Comparator (Ustekinumab) in Patients With Moderate to Severe Chronic Plaque Psoriasis
NCT02684357 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT00237887 ·Status: COMPLETED ·Phase: PHASE3
-
A Safety and Effectiveness Study of CNTO 1275 in Patients With Moderate to Severe Plaque-type Psoriasis
NCT00320216 ·Status: COMPLETED ·Phase: PHASE2
-
Double-blind, Randomised, Placebo-controlled Trial Investigating BIRT 2584 XX in Patients With Moderate/Severe Psoriasis
NCT00333411 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Mirikizumab (LY3074828) in Participants With Moderate to Severe Plaque Psoriasis
NCT02899988 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate Efficacy and Safety of IBI112 in Adolescent Participants With Moderate to Severe Plaque Psoriasis
NCT07265284 ·Status: RECRUITING ·Phase: PHASE3
-
A Trial Comparing SHR-1139 Injection With Placebo in Patients With Moderate-to-severe Plaque Psoriasis
NCT06875934 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
International Clinical Trial to Evaluate Efficacy and Safety of Multiple Subcutaneous Injections of BCD-085 in Various Doses in Patients With Moderate to Severe Plaque Psoriasis
NCT02762994 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Safety and Efficacy of Infliximab in Patients With Psoriasis
NCT00106834 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Placebo and an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT03370133 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
NCT00235820 ·Status: COMPLETED ·Phase: PHASE3