Study of Ranibizumab Administered in Conjunction With Photodynamic Therapy With Verteporfin in Patients With Subfoveal Choroidal Neovascularization and Age-Related Macular Degeneration
NCT00288561 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2008-06-19
Summary
Ranibizumab is derived from a murine monoclonal anti- vascular endothelial growth factor (VEGF) antibody and can penetrate through the many retinal cell layers following intravitreal injection. The present study is directed towards the assessment of ranibizumab administered on the same day in combination with verteporfin in patients with subfoveal CNV secondary to ARMD
Conditions
- Age-Related Macular Degeneration (ARMD)
Interventions
- DRUG
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Customer Information · Novartis - Including Sites in Germany
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-11-30
- Completion
- 2007-07-31
Countries
- Switzerland
Study Locations
More Related Trials
-
Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia
NCT01217944 ·Status: COMPLETED ·Phase: PHASE3
-
Verteporfin Photodynamic Therapy Administered in Conjunction With Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD)
NCT00433017 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Safety and Tolerability of Ranibizumab in Mono/Bilateral Wet Age Related Macular Degeneration (w-AMD) Patients in Eyes With BCVA<2/10 and/or 2nd Affected Eye
NCT01986907 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Two Treatment Regimens of 0.5 mg Ranibizumab Intravitreal Injections Guided by Functional and/or Anatomical Criteria, in Patients With Neovascular Age-related Macular Degeneration
NCT01780935 ·Status: COMPLETED ·Phase: PHASE3
-
Randomized Study for Efficacy and Safety of Ranibizumab 0.5mg in Treat-extend and Monthly Regimens in Patients With nAMD
NCT01948830 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate Ranibizumab in Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)
NCT00251459 ·Status: COMPLETED ·Phase: PHASE3
-
Ranibizumab in Hemorrhagic Choroidal Neovascularization Trial
NCT00363168 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Ranibizumab 0.5 vs Verteporfin PDT in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia
NCT01922102 ·Status: COMPLETED ·Phase: PHASE3
-
Assess the Efficacy/Safety of Intravitreal Ranibizumab in Patients With Vision Loss Due to Choroidal Neovascularization.
NCT01840410 ·Status: COMPLETED ·Phase: PHASE3
-
Ranibizumab Intravitreal Injections in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion
NCT01535261 ·Status: COMPLETED ·Phase: PHASE3
-
Prophylactic Ranibizumab for Exudative Age-related Macular Degeneration
NCT02140151 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Evaluation of Safety and Efficacy of Once Monthly Ranibizumab Injections in Chinese Patients With Wet Age Related Macular Degeneration (AMD) Patients
NCT00826371 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate rhuFab V2 in Subjects With Minimally Classic or Occult Subfoveal Neovascular Macular Degeneration
NCT00056836 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy Study of Ranibizumab on Patients With Age-related Macular Degeneration.
NCT01831947 ·Status: COMPLETED ·Phase: PHASE4
-
Reduced-fluence Verteporfin Photodynamic Therapy Plus Ranibizumab for Choroidal Neovascularization in Pathologic Myopia
NCT01968486 ·Status: COMPLETED ·Phase: PHASE1
-
Ranibizumab for Treating Submacular Vascularized Pigment Epithelial Detachments
NCT00749021 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison of Treatment Regimens Using Ranibizumab: Intensive (Resolution of Intra- and Sub-retinal Fluid) vs Relaxed (Resolution of Intra-retinal Fluid and/or Sub-retinal Fluid >200µm at the Foveal Centre)
NCT01972789 ·Status: COMPLETED ·Phase: PHASE4
-
Ranibizumab Treatment for Retinal Vein Occlusion
NCT01968616 ·Status: UNKNOWN ·Phase: NA
-
A Study to Compare rhuFab V2 With Verteporfin Photodynamic in Treating Subfoveal Neovascular Macular Degeneration
NCT00061594 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Ranibizumab Monotherapy and Ranibizumab Combination Therapies in Recurrent or Persistent Choroidal Neovascularization Secondary to Age-related Macular Degeneration
NCT01162746 ·Status: COMPLETED ·Phase: PHASE2
-
Combination of Ranibizumab and Verteporfin Therapy in Neovascular Age-related Macular Degeneration
NCT00967213 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Ranibizumab Administered Monthly or on an As-needed Basis in Patients With Subfoveal Neovascular Age-related Macular Degeneration (HARBOR)
NCT00891735 ·Status: COMPLETED ·Phase: PHASE3
-
Ranibizumab for the Treatment of Choroidal Neovascularisation (CNV) Secondary to Pathological Myopia (PM): an Individualized Regimen
NCT01037348 ·Status: COMPLETED ·Phase: PHASE2
-
EXTEND III - Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)
NCT00470678 ·Status: COMPLETED ·Phase: PHASE3
-
601 Versus Ranibizumab in Patients With Pathological Myopic Choroidal Neovascularization (pmCNV)
NCT04922151 ·Status: UNKNOWN ·Phase: PHASE2