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Autoimmune Dysregulation in Pigmentary Glaucoma

NCT00280345 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2023-12-15

No results posted yet for this study

Summary

Based on these recent observations and findings in this new animal model of pigmentary glaucoma in the DBA/2J mouse, we propose that immune system abnormalities in the anterior chamber may play a possible role in the development of pigmentary glaucoma and possibly primary open-angle glaucoma (POAG) in humans.

Conditions

  • Pigmentary Glaucoma
  • Primary Open Angle Glaucoma
  • Cataract

Interventions

PROCEDURE

Trabeculectomy

A surgical procedure used in the treatment of glaucoma to relieve intraocular pressure by removing part of the eye's trabecular meshwork

PROCEDURE

Trabeculectomy and cataract surgery

A surgical procedure used in the treatment of glaucoma to relieve intraocular pressure by removing part of the eye's trabecular meshwork and the removal of the cataract

PROCEDURE

Cataract surgery

Removal of the cataract from the eye

Sponsors & Collaborators

  • University of Oklahoma

    lead OTHER

Principal Investigators

  • Crystal McAfee, MA-HHSA · Dean A. McGee Eye Institute

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-02-28
Primary Completion
2007-09-30
Completion
2009-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00280345 on ClinicalTrials.gov