Sorafenib in Treating Patients With Recurrent Non-Hodgkin's Lymphoma
NCT00278382 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 33
Last updated 2013-02-07
Summary
Sorafenib may stop the growth of cancer cells by blocking blood flow to the cancer and by blocking some of the enzymes needed for cell growth. This phase II trial is studying how well sorafenib works in treating patients with chemosensitive recurrent aggressive non-Hodgkin's lymphoma
Conditions
- Anaplastic Large Cell Lymphoma
- Recurrent Adult Diffuse Large Cell Lymphoma
- Recurrent Mantle Cell Lymphoma
Interventions
- DRUG
-
sorafenib tosylate
Given orally
- OTHER
-
laboratory biomarker analysis
Correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Meyer Heyman · University of Maryland Greenebaum Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-10-31
- Primary Completion
- 2007-12-31
Countries
- United States
Study Locations
More Related Trials
-
Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers
NCT02978625 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
NCT00290472 ·Status: COMPLETED ·Phase: PHASE2
-
A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-Cell Lymphoma Patients
NCT01561833 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy & Lenalidomide in Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma
NCT02561273 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
NCT00365274 ·Status: TERMINATED ·Phase: PHASE2
-
Fenretinide Lym-X-Sorb™ in Treating Patients With Recurrent or Resistant Solid Tumors or Lymphoma
NCT00589381 ·Status: COMPLETED ·Phase: PHASE1
-
S9911, Combination Chemotherapy Plus Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma
NCT00003784 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine for CD30-Positive Malignancies
NCT00649584 ·Status: TERMINATED ·Phase: PHASE1
-
CCI-779 in Treating Patients With Mantle Cell Non-Hodgkin's Lymphoma
NCT00033267 ·Status: COMPLETED ·Phase: PHASE2
-
BAY 59-8862 in Treating Patients With Refractory Non-Hodgkin's Lymphoma
NCT00039156 ·Status: UNKNOWN ·Phase: PHASE2
-
506U78 in Treating Patients With Recurrent or Refractory Cutaneous T-cell Lymphoma
NCT00005982 ·Status: TERMINATED ·Phase: PHASE2
-
Study of SGN-40 in Patients With Relapsed Diffuse Large B-Cell Lymphoma
NCT00435916 ·Status: COMPLETED ·Phase: PHASE2
-
SG2501 Safety Study in Subjects with Relapsed or Refractory Hematological Malignancies and Lymphoma.
NCT05293912 ·Status: TERMINATED ·Phase: PHASE1
-
CC-486 and Nivolumab for the Treatment of Hodgkin Lymphoma Refractory to PD-1 Therapy or Relapsed
NCT05162976 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma
NCT05077527 ·Status: RECRUITING ·Phase: PHASE1
-
Gallium Nitrate in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma
NCT00002578 ·Status: COMPLETED ·Phase: PHASE2
-
Study of BGB-11417 Monotherapy in Participants With Relapsed or Refractory Mantle Cell Lymphoma
NCT05471843 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Aminocamptothecin in Treating Patients With Refractory or Recurrent Hodgkin's Disease or Non-Hodgkin's Lymphoma
NCT00002745 ·Status: COMPLETED ·Phase: PHASE2
-
Investigation of Safety, Tolerability and Maximum Tolerated Dose (MTD) of BI 2536 in Patients With Recurrent Advanced Aggressive Non-Hodgkin's Lymphoma (NHL)
NCT00243087 ·Status: COMPLETED ·Phase: PHASE1
-
Avelumab for Recurrent/Metastatic Nasopharyngeal Cancer
NCT02875613 ·Status: TERMINATED ·Phase: PHASE2
-
Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy
NCT01332279 ·Status: WITHDRAWN ·Phase: PHASE1
-
SB-715992 in Treating Patients With Metastatic or Unresectable Solid Tumors or Hodgkin's or Non-Hodgkin's Lymphoma
NCT00101244 ·Status: TERMINATED ·Phase: PHASE1
-
Oral LBH589 in Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL)
NCT01090973 ·Status: TERMINATED ·Phase: PHASE2
-
Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
NCT01278615 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine in Treating Patients With Newly Diagnosed, Relapsed, or Chemotherapy-Resistant Mantle Cell Lymphoma
NCT00234026 ·Status: COMPLETED ·Phase: PHASE2