Gemcitabine and Oxaliplatin Followed By Radiation Therapy, Fluorouracil, and Oxaliplatin in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery
NCT00275119 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2009-02-09
Summary
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, oxaliplatin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving chemotherapy together with radiation therapy may kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving gemcitabine together with oxaliplatin followed by radiation therapy, fluorouracil, and oxaliplatin works in treating patients with locally advanced pancreatic cancer that cannot be removed by surgery.
Conditions
Interventions
- DRUG
- DRUG
-
gemcitabine hydrochloride
- DRUG
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
GERCOR - Multidisciplinary Oncology Cooperative Group
lead OTHER
Principal Investigators
-
Laurence Moureau-Zabotto, MD · Institut Paoli-Calmettes
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-11-30
Countries
- France
Study Locations
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