A Clinical Trial of Infliximab for Uveitis
NCT00273390 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2011-07-04
Summary
This project is designed to test the hypothesis that inhibition of binding between tumor necrosis factor alpha (TNF-alpha) and its receptors using Remicade (infliximab, chimeric mouse/human IgG1K monoclonal antibody directed against human TNF-alpha, Centocor, Malvern,PA) is clinically useful for patients with uveitis that is refractory to other forms of systemic immunosuppressive therapy.
Conditions
- Uveitis
Interventions
- DRUG
-
Remicade (infliximab)
Sponsors & Collaborators
-
Centocor, Inc.
collaborator INDUSTRY -
Oregon Health and Science University
lead OTHER
Principal Investigators
-
James T Rosenbaum, MD · Oregon Health and Science University
-
Eric B Suhler, MD · Oregon Health and Science University
-
Justine Smith, MBBS, Phd · Oregon Health and Science University
Eligibility
- Min Age
- 9 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-08-31
- Primary Completion
- 2006-12-31
- Completion
- 2006-12-31
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