MedTrace Logo

Early Evaluation of the Response of Large B Cell Non Hodgkin's Lymphoma to Chemotherapy by PET/CT

NCT00256490 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 82

Last updated 2024-12-09

No results posted yet for this study

Summary

Patients affected with non-Hodgkin's large B-cell lymphoma are treated by chemotherapy. The evaluation of the response to this treatment is made by Positron Emission Tomography (PET/CT) in many centres where this technology is available. Presently PET scans and CT scans are being performed before treatment, after 4 cycles of chemotherapy and a few months after the end of treatment.

The goal of this study is to determine if it is possible to evaluate the efficiency of chemotherapy treatments after one cycle of treatment instead of waiting after 4 cycles, using a new scanner that combines PET and CT modalities. Data available from studies on these combined exams suggest that PET/CT helps to rapidly evaluate the response of the chemotherapy treatment. We also want to verify if some pathological characteristics measured from tumor cells will enable doctors to predict in advance the response to treatment.

Conditions

  • Lymphoma, Large-Cell

Interventions

PROCEDURE

PET/CT 20 days after the first cycle of chemotherapy

Sponsors & Collaborators

  • Eric Turcotte

    lead OTHER

Principal Investigators

  • Eric Turcotte, MD, FRCPC · Centre de recherche du Centre hospitalier universitaire de Sherbrooke

  • Francois Bénard, MD, FRCPC · Centre de recherche du Centre hospitalier universitaire de Sherbrooke

  • Virginie Bruneau, MD · Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-11-30
Primary Completion
2009-12-01
Completion
2009-12-01

Countries

  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00256490 on ClinicalTrials.gov