Previously Untreated Advanced Non-Small Cell Lung Cancer (NSCLC)
NCT00254319 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2005-11-16
Summary
Avastin is a novel antiangiogenic agent that has recently been shown to improve response rates and survival of patients with advanced nonsquamous non-small cell lung cancer when added to front-line carboplatin/paclitaxel chemotherapy, and is now being routinely incorporated into the treatment of these patients. Alimta is a recently approved chemotherapeutic that has shown activity against non-small cell lung cancer when given alone and in combination with carboplatin, has a favorable toxicity profile andrequires only a brief (10 minute) infusion time. Therefore we propose to study the combination of Avasin, Alimta, and Carboplatin administered as front-line therapy to patients with advanced nonsquamous non-small cell lung cancer.
Conditions
- Untreated Advanced Non-Small Cell Lung Cancer
Interventions
- DRUG
-
Avastin, Alimta
Sponsors & Collaborators
-
The Cooper Health System
lead OTHER
Principal Investigators
-
James Stevenson, M.D. · The Cooper Health System
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
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