Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients
NCT00248053 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2012-09-20
Summary
The purpose of this study is to assess if curcumin, a commonly used food spice, can regress colorectal adenomatous polyps in patients with familial adenomatous polyposis, an inherited form of colorectal cancer.
Conditions
Interventions
- DRUG
-
curcumin
curcumin 500 mg by mouth, three times a day for 9 months
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Francis M Giardiello, M.D. · Johns Hopkins University
Study Design
- Allocation
- NON_RANDOMIZED
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-11-30
- Primary Completion
- 2008-06-30
More Related Trials
-
Niclosamide for Familial Adenomatous Polyposis
NCT04296851 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis
NCT06545526 ·Status: RECRUITING ·Phase: PHASE3
-
An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis
NCT06557733 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Rofecoxib in Familial Adenomatous Polyposis (FAP) (0966-205)(TERMINATED)
NCT00140894 ·Status: TERMINATED ·Phase: PHASE4
-
A Study of JNJ-64251330 in Participants With Familial Adenomatous Polyposis
NCT05014360 ·Status: COMPLETED ·Phase: PHASE1
-
Testing Obeticholic Acid for Familial Adenomatous Polyposis
NCT05223036 ·Status: TERMINATED ·Phase: PHASE2
-
Sirolimus and Familial Adenomatous Polyposis (FAP)
NCT03095703 ·Status: COMPLETED ·Phase: PHASE2
-
Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01
NCT04674228 ·Status: COMPLETED
-
Preventive Anti-inflammatory Diet to Reduce Gastro-intestinal Inflammation in FAP Patients: a Prospective Pilot Study
NCT04552405 ·Status: COMPLETED ·Phase: NA
-
The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
NCT01725490 ·Status: COMPLETED ·Phase: PHASE2
-
Prevention of Colorectal Sporadic Adenomatous Polyps (PRESAP)
NCT00141193 ·Status: COMPLETED ·Phase: PHASE3
-
Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program
NCT02747862 ·Status: COMPLETED
-
Microbial and Environmental Factors Associated with Polyps Development in Familial Adenomatous Polyposis (MicrobEnvironment in FAP)
NCT06614738 ·Status: RECRUITING
-
Effect of 2 Doses of EPA on Apoptosis and Cell Proliferation on Colon Mucosa
NCT00432913 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Ursodeoxycholic Acid in the Treatment of Duodenal Adenomas in Familial Adenomatous Polyposis (FAP) Patients
NCT00134758 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Coxib-inhibition of Duodenal Polyp Growth in FAP
NCT00844727 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Chromocolonoscopy for the Detection of Flat Adenomas in Routine Colorectal Cancer Screening.
NCT00245492 ·Status: COMPLETED ·Phase: NA
-
Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis
NCT03806426 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Molecular Fluorescence Endoscopy in Patients With Familial Adenomatous Polyposis, Using Bevacizumab-IRDye800CW
NCT02113202 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy of Vitamin B1 in Familial Adenomatous Polyposis Patients.
NCT06649825 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis
NCT04677998 ·Status: RECRUITING
-
Computer Assisted Optical Assessment of Small Colorectal Polyps
NCT02522702 ·Status: UNKNOWN
-
Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis
NCT03471403 ·Status: RECRUITING
-
Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
NCT01483144 ·Status: COMPLETED ·Phase: PHASE3
-
The Utility of Cap Colonoscopy in Increasing Adenoma Detection Rate
NCT01601431 ·Status: TERMINATED ·Phase: NA