Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia Patients
NCT00235560 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2024-02-29
Summary
These study is designed to evaluate the tolerability and efficacy of sirolimus (rapamycin) in combination with low-dose aracytin in elderly AML.
Conditions
Interventions
- DRUG
-
sirolimus
Sponsors & Collaborators
-
French Innovative Leukemia Organisation
collaborator OTHER -
University Hospital, Toulouse
lead OTHER
Principal Investigators
-
RECHER Christian · University Hospital, Toulouse
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-06-30
- Primary Completion
- 2008-06-30
- Completion
- 2008-06-30
Countries
- France
Study Locations
More Related Trials
-
Adding Lomustine to Chemotherapy in Older Patients With Acute Myelogenous Leukemia (AML), and Allogeneic Transplantation for Patients From 60 to 65 Years Old
NCT00590837 ·Status: COMPLETED ·Phase: PHASE3
-
Gemtuzumab Ozogamicin+Cytarabine vs Idarubicin+Cytarabine in Elderly Patients With AML.Mylofrance 4
NCT02473146 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Sirolimus in Combination With MEC in High Risk Myeloid Leukemias
NCT00780104 ·Status: COMPLETED ·Phase: PHASE1
-
Venetoclax + Cytarabine Versus Idarubicin + Cytarabine : Efficacity Assessment as Post-remission Therapy to Elderly Patients With Acute Myeloid Leukemia in First Remission
NCT04968015 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
DNR and AraC Combined to Fractionated Mylotarg® in Patients With First Relapse of AML
NCT02182596 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Clofarabine, Idarubicin, and Cytarabine Combination in Acute Myeloid Leukemia (AML) Induction
NCT01025154 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Relapsed Acute Myelogenous Leukemia
NCT00003758 ·Status: UNKNOWN ·Phase: PHASE2
-
Clofarabine and Temsirolimus in Treating Older Patients With Relapsed or Refractory Acute Myeloid Leukemia
NCT00775593 ·Status: COMPLETED ·Phase: PHASE2
-
Clofarabine/Ara-C Treatment Combined With Reduced-intensity Conditioning Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia in Primary Treatment Failure
NCT01188174 ·Status: COMPLETED ·Phase: PHASE2
-
DLAAG in the Treatment of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome With Blast Excess
NCT03356080 ·Status: UNKNOWN ·Phase: PHASE2
-
All-Trans Retinoic Acid in Combination With Standard Induction and Consolidation Therapy in Older Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT00151255 ·Status: COMPLETED ·Phase: PHASE3
-
S0112 Cytarabine and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia
NCT00023777 ·Status: COMPLETED ·Phase: PHASE2
-
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
NCT06459024 ·Status: RECRUITING
-
Early Tapering of Immunosuppressive Agents to Immunomodulation to Improve Survival of AML Patients
NCT03150134 ·Status: UNKNOWN ·Phase: PHASE4
-
Treatment Outcome in Elderly Patients
NCT00700544 ·Status: COMPLETED ·Phase: PHASE3
-
Assessing Refractoriness and Infectious Survival Events in AML
NCT06709235 ·Status: COMPLETED
-
Therapy of Acute Myeloid Leukemia in Patients Over the Age of 60 : DA Versus Mitoxantrone With Intermittent AraC
NCT00180167 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of an Adult Acute Lymphoblastic Leukemia Chemotherapy for Adult Lymphoblastic Lymphoma
NCT00195871 ·Status: UNKNOWN ·Phase: PHASE2
-
Targeting Leukemic Stem Cell Expressing the IL-1RAP Protein in Chronic Myelogenous Leukemia (CML)
NCT02842320 ·Status: COMPLETED ·Phase: NA
-
Clofarabine Plus Cytarabine in Patients With Previously Untreated Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome
NCT00065143 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment of Acute Lymphoblastic Leukemia (ALL) in Younger Adults
NCT00327678 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Acute Myeloid Leukemia (AML) in Adults 50 to 70 Years, Study of Two Anthracyclines and the Interest of Maintenance Treatment With Interleukin 2
NCT00931138 ·Status: COMPLETED ·Phase: PHASE3
-
Total Body Irradiation and Cladribine Before Allogeneic Hematopoietic Cell Transplantation in Patients With AML (Acute Myeloid Leukemia) and Myelodysplastic Syndromes
NCT04861207 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Laromustine, Daunorubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia
NCT00840684 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Lenalidomide in Combination With Microtransplantation as Post-remission Therapy in AML
NCT02255162 ·Status: TERMINATED ·Phase: PHASE1