MedTrace Logo

Clinical and Molecular Characterization of Familial Microsatellite Stable Colorectal Cancer

NCT00220246 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 130

Last updated 2007-03-01

No results posted yet for this study

Summary

Two major genetic pathways leading to colorectal carcinoma can well be distinguished; the 'suppressor pathway', which is characterized by inactivation of tumor-suppressor genes and the 'mutator pathway', which is characterized by microsatellite instability. The purpose of this study is to explore a third putative pathway; microsatellite and chromosome stable colorectal cancer where an alternative cancer-causative mechanism might play a role.

Conditions

  • Colorectal Neoplasms

Sponsors & Collaborators

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • Nicoline Hoogerbrugge, MD, PhD · Department of Human Genetics, Radboud University Nijmegen Medical Center

Eligibility

Max Age
51 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-03-31
Completion
2008-09-30

Countries

  • Netherlands

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00220246 on ClinicalTrials.gov