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myoARRAY and TcLandscape Analysis for the Diagnosis of Inflammatory Myopathies

NCT00213629 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2012-02-16

No results posted yet for this study

Summary

The diagnosis of the different forms of inflammatory myopathies (polymyositis, dermatomyositis, inclusion-body myositis...) remains difficult which may lead to unappropriate patient care.

Objective 1 : to develop and evaluate the diagnostic value of a dedicated DNA-array (myoARRAY) for adult-onset muscular diseases with focus on inflammatory myopathies.

Objective 2 : to evaluate the diagnostic value of T cell repertoire (TcLand) analysis to distinguish different forms of inflammatory myopathies.

Conditions

  • Polymyositis
  • Dermatomyositis

Interventions

OTHER

transcriptome analysis

transcriptome analysis from muscle biopsy

OTHER

T cell repertoire analysis

blood T cell repertoire analysis

Sponsors & Collaborators

  • Association Française contre les Myopathies (AFM), Paris

    collaborator OTHER

  • University Hospital, Rouen

    lead OTHER

Principal Investigators

  • Olivier Boyer, MD, PhD · University Hospital, Rouen

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
76 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-11-30
Primary Completion
2010-07-31
Completion
2010-07-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00213629 on ClinicalTrials.gov