The Role of Naive T-Cells in HIV Pathogenesis
NCT00206531 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 75
Last updated 2006-10-04
Summary
While HIV mainly infects mature T-cells it can also infect newly produced (or naïve) T-cells. These infected naïve T cells may then act a viral reservoir even in patients with undetectable viral loads. Understanding when and how these cells are infected is important because it could help us to understand why patients fail therapy even if they have a persistently undetectable viral load.
Conditions
- HIV Infections
Sponsors & Collaborators
-
Bayside Health
lead OTHER_GOV
Principal Investigators
-
Sharon R Lewin · Director, Infectious Diseases Unit, The Alfred Hospital
-
Jenny Hoy · Head Clinical Research Unit, Infectious Diseases Unit, Alfred Hospital
Eligibility
- Min Age
- 0 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
Countries
- Australia
Study Locations
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