A Pilot Study to Examine the Feasibility and Effect of Tumor Necrosis Factor (TNF) Inhibition on HIV Disease
NCT00205231 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2019-03-22
Summary
This pilot study will investigate the safety and effect of etanercept in HIV infection by studying HIV replication and immune function (as measured by CD4 counts) in individuals with HIV infection.
Conditions
- HIV Infections
Interventions
- DRUG
-
etanercept
Sponsors & Collaborators
-
Immunex Corporation
collaborator INDUSTRY -
University of Wisconsin, Madison
lead OTHER
Principal Investigators
-
Andrew Urban, MD · University of Wisconsin, Madison
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-05-31
- Primary Completion
- 2004-05-01
- Completion
- 2004-05-01
Countries
- United States
Study Locations
More Related Trials
-
Evaluation of the Safety and Tolerance of Immunotherapy With Autologous, Ex-Vivo Expanded, HIV-Specific Cytotoxic T-Cells in HIV-Infected Patients With CD4+ Counts Between 100-400/mm3
NCT00000756 ·Status: COMPLETED ·Phase: PHASE1
-
Safety of and Immune System Response to an HIV Vaccine (EP HIV-1090) in HIV Infected Patients
NCT00052182 ·Status: COMPLETED ·Phase: PHASE1
-
Immune Responses to Pneumococcal Vaccination Among HIV-infected Subjects
NCT00706550 ·Status: COMPLETED ·Phase: NA
-
A Study of the Safety and Antiretroviral Activity of 3BNC117
NCT02588586 ·Status: COMPLETED ·Phase: PHASE2
-
Selection of a Protective T Cell-based HIV-1/FIV Vaccine
NCT02389595 ·Status: ACTIVE_NOT_RECRUITING
-
Safety of and Immune System Response to an HIV Vaccine (EP HIV-1090) in HIV Uninfected Adults
NCT00054860 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study
NCT00002037 ·Status: COMPLETED ·Phase: NA
-
Safety and Immunogenicity Study of AIDS Vaccine (Combined Use of DNA Vaccine and Recombinant Vaccinia Virus Tiantan)
NCT01705223 ·Status: COMPLETED ·Phase: PHASE2
-
Safety of and Immune Response to an HIV DNA Plasmid Vaccine Followed by HIV Adenoviral Vector Vaccine in Healthy African Adults
NCT00415649 ·Status: WITHDRAWN ·Phase: PHASE2
-
Immune Response to Pneumococcal Vaccination in HIV Infected Individuals
NCT02515240 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control During Analytic Treatment Interruption
NCT04340596 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Using the Drug Thalidomide to Stimulate T Cells in HIV-Infected People
NCT00053430 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Safety and Immunogenicity Study of HIV p17/p24:Ty-VLP in HIV-1 Seronegative Subjects
NCT00001053 ·Status: COMPLETED ·Phase: PHASE1
-
A Pilot Study of Allogeneic Lymphocyte Transfer in HIV Infection
NCT00000852 ·Status: COMPLETED ·Phase: NA
-
Rapid Build of HIV Related Protective Barriers
NCT03852849 ·Status: UNKNOWN ·Phase: NA
-
Interluekin-7 to Treat HIV-Infected People Receiving Antiretroviral Treatment
NCT00105417 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults Infected With Human Immunodeficiency Virus (HIV) (V114-018)
NCT03480802 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluating the Safety and Immune Response to Three HIV Vaccine Schedules in Healthy, HIV-Uninfected Adults
NCT01783977 ·Status: COMPLETED ·Phase: PHASE1
-
Twins Study of Gene Therapy for HIV Infection
NCT00001535 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluating the Safety of and Immune Response to an HIV Vaccine in Healthy, HIV-Uninfected Adults in Uganda
NCT01549470 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Thalidomide in HIV-Infected Patients Who Are Receiving HAART
NCT00002392 ·Status: COMPLETED ·Phase: NA
-
Safety and Immunogenicity of Recombinant HIV Vaccines for HIV/AIDS
NCT01881581 ·Status: UNKNOWN ·Phase: PHASE1
-
Double Blind Study of Thymopentin Effects on Patients With HIV-1 Infection
NCT00002051 ·Status: COMPLETED ·Phase: NA
-
HVTN Protocol 204 - A Phase II Clinical Trial to Evaluate the Safety and Immunogenicity of a Multiclade HIV-1 DNA Plasmid Vaccine, VRC-HIVDNA016-00-VP, Followed by a Multiclade Recombinant Adenoviral Vector HIV-1 Vaccine Boost, VRCHIVADV014-00-VP, in HIV-1 Uninfected Adult Participants
NCT00125970 ·Status: COMPLETED ·Phase: PHASE2
-
Prevention of Varicella Zoster Virus (VZV)-Reactivation in HIV-positive Individuals Enrolled in a Prospective Immunogenicity and Safety Trial of VZV Vaccine: PROVE-IT-Study
NCT01213810 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2