Intradermal Vaccination With Stabilized Tumor mRNA - a Clinical Phase I/II Trial in Melanoma Patients
NCT00204607 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2007-04-19
Summary
vaccination protocol to induce specific immune responses against melanoma associated antigens by intradermal injections of mRNA coding for the corresponding antigen
Conditions
- Malignant Melanoma
Interventions
- BIOLOGICAL
-
mRNA
- DRUG
-
GM-CSF s.c.
Sponsors & Collaborators
-
University Hospital Tuebingen
lead OTHER
Principal Investigators
-
Claus Garbe, Prof. Dr. · University of Tuebingen, Department of dermatology
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-07-31
- Completion
- 2007-01-31
Countries
- Germany
Study Locations
More Related Trials
-
Vaccine Therapy in Treating Patients With Stage IV Melanoma
NCT00126685 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Stage IV or Recurrent Melanoma
NCT00012064 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Local Treatment of Metastatic Melanoma With Autologous Lymphocytes and the Bispecific Antibody rM28
NCT00204594 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma
NCT00006385 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery
NCT00089206 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019214 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Unresectable Metastatic Melanoma
NCT00004148 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy Followed by Biological Therapy in Treating Patients With Stage III or Stage IV Melanoma
NCT00006113 ·Status: TERMINATED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma
NCT00104845 ·Status: COMPLETED ·Phase: PHASE1
-
Melanoma Vaccine in Treating Patients With Stage III Melanoma After Surgery to Remove Lymph Nodes
NCT01082198 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Advanced Melanoma
NCT00705640 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma
NCT00398073 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019721 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic Melanoma
NCT00071981 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00334776 ·Status: COMPLETED ·Phase: PHASE2
-
Multiepitope Peptide Vaccination in Melanoma
NCT00153569 ·Status: UNKNOWN ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Stage IV Cutaneous Melanoma
NCT00074230 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With High-Risk Stage III or Completely Resected Metastatic Melanoma
NCT00019890 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Stage II Melanoma That Can Be Removed by Surgery
NCT00003274 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00002817 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma That Has Not Responded to Previous Treatment
NCT00022438 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma
NCT00053391 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Melanoma
NCT00020358 ·Status: COMPLETED ·Phase: PHASE2
-
Immunotherapy of Stage III/IV Melanoma Patients
NCT00112242 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy and Monoclonal Antibody Therapy in Treating Patients With Stage IV Melanoma
NCT00032045 ·Status: COMPLETED ·Phase: PHASE2