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Efficacy of Pre- and Post-Operative Oral Dextromethorphan

NCT00199303 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2005-09-20

No results posted yet for this study

Summary

We studied the effect of dextromethorphan (DEX), an N-methyl-d-aspartate antagonist, on analgesic consumption and pain scoring after abdominal hysterectomy. Our aim was to compare the analgesic effectiveness and incidence of adverse side effects of oral DEX with placebo (P)

Conditions

  • Efficacy of Dextromethorphan
  • Morphine Consumption
  • Pain

Interventions

DRUG

pre-operatively followed by 30 mg three times per day after surgery

Sponsors & Collaborators

  • Khon Kaen University

    lead OTHER

Principal Investigators

  • waraporn chau-in, Asso Prof. · Department of Anesthesiology, Faculty of Medicine,KhonKaen University,KhonKaen 40002, Thailand

  • BUSABONG SUKMOUEN, Dr. · Department of Anesthesiology

  • KRIANGSAK NGAMSANGSIRISAPT, Dr. · Department of Anesthesiology

  • WINITA JIRARAREUNGSAK · Department of Anesthesiology

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
60 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2002-12-31
Completion
2003-12-31

Countries

  • Thailand

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00199303 on ClinicalTrials.gov