FRAGRANCE Part A Safety: Study to Find a Genetic Signature of de Novo Resistance to Letrozole
NCT00199134 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 49
Last updated 2015-01-06
Summary
Find a genetic signature of de novo resistance to letrozole in adjuvant breast cancer;
Conditions
Interventions
- DRUG
-
Size of the tumor is followed
Sponsors & Collaborators
-
Feculdade de Medicina da Universidade de Sao Paulo - Brasil
collaborator OTHER -
Hospital de Clinicas de Porto Alegre
collaborator OTHER -
Hospital do Cancer, Sao Paulo
collaborator OTHER -
Jules Bordet Institute
lead OTHER
Principal Investigators
-
Christos Sotiriou, MD, PhD · Jules Bordet Institute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-11-30
- Primary Completion
- 2014-12-31
- Completion
- 2014-12-31
Countries
- Belgium
Study Locations
More Related Trials
-
Letrozole in Preventing Breast Cancer in Healthy Postmenopausal Women at High Risk for Breast Cancer
NCT01077453 ·Status: COMPLETED ·Phase: PHASE1
-
Letrozole in Postmenopausal Women at Increased Risk for Breast Cancer
NCT00280930 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Outcomes After Letrozole Treatment According to the Estrogen Receptor Expression in Postmenopausal Women
NCT01069211 ·Status: UNKNOWN
-
Letrozole in Preventing Breast Cancer in Postmenopausal Women With a BRCA1 or BRCA2 Mutation
NCT00673335 ·Status: COMPLETED ·Phase: PHASE3
-
Open Label Study of Postmenopausal Women With ER and /or PgR Positive Breast Cancer Treated With Letrozole
NCT00237224 ·Status: COMPLETED ·Phase: PHASE4
-
Letrozole in Preventing Breast Cancer in Postmenopausal Women Who Are at Increased Risk for Breast Cancer Due to High Breast Density
NCT00238316 ·Status: COMPLETED ·Phase: PHASE2
-
Study of High-dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer
NCT00237211 ·Status: COMPLETED ·Phase: PHASE2
-
Letrozole in Preventing Breast Cancer in Postmenopausal Women
NCT00090857 ·Status: COMPLETED ·Phase: PHASE2
-
Letrozole and Imatinib Mesylate in Treating Postmenopausal Participants With Estrogen or Progesterone Positive Metastatic Breast Cancer
NCT00338728 ·Status: COMPLETED ·Phase: PHASE2
-
Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer
NCT03747042 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Safety and Efficacy of Letrozole Monotherapy as Second-line Endocrine Therapy in Postmenopausal Patients With Advanced Breast Cancer Who Received Previous Anti-estrogen Treatment
NCT00237198 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Predictive Factors Regarding the Effectivity of Aromatase Inhibitor Therapy (PreFace)
NCT01908556 ·Status: UNKNOWN ·Phase: PHASE4
-
Extension Study of 1.0mg Dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer
NCT00247663 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Rheumatologic Tolerability of Letrozole in Postmenopausal Patients With Hormone Receptor Positive Breast Cancer
NCT00329940 ·Status: COMPLETED ·Phase: PHASE3
-
Letrozole in Treating Postmenopausal Women With Stage I, II or III Breast Cancer That Can Be Removed by Surgery
NCT00651976 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Trial of Endocrine Against Locoregional Therapy First in Postmenopausal Women With Early Breast Cancer
NCT00908531 ·Status: TERMINATED ·Phase: PHASE3
-
Letrozole and Goserelin or Leuprolide in Treating Premenopausal Estrogen Receptor-Positive Patients With Stage IV Breast Cancer
NCT00498901 ·Status: TERMINATED ·Phase: PHASE2
-
An Examination of Predictors of Indicators of Response to Letrozole 2.5 mg
NCT00291109 ·Status: COMPLETED
-
Letrozole as Early Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer
NCT00332852 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause
NCT06465368 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I/II Trial of Letrozole and Sorafenib in Post-Menopausal Hormone-Receptor + Breast Cancer
NCT00634634 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Neoadjuvant Letrozole in Treating Postmenopausal Women With Estrogen-Receptor Positive and/or Progesterone-Receptor Positive Stage II, Stage IIIA, or Stage IIIB Breast Cancer
NCT00084396 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Hormone Therapy With Letrozole in Postmenopausal Women With Breast Cancer
NCT00330317 ·Status: COMPLETED ·Phase: PHASE3
-
Letrozole in Preventing Cancer in Postmenopausal Women Who Have Received 4-6 Years of Hormone Therapy for Hormone Receptor-Positive, Lymph Node-Positive, Early-Stage Breast Cancer
NCT00553410 ·Status: COMPLETED ·Phase: PHASE3
-
Fertility Preservation in Breast Cancer Patients
NCT02661932 ·Status: COMPLETED ·Phase: PHASE4