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Development of Resistance Mutations in Pregnant HIV-positive (+) Women Following Perinatal Antiretroviral Therapy in Israel

NCT00197366 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2017-11-28

No results posted yet for this study

Summary

It has been shown that treatment of HIV-positive women with antiretroviral medication during pregnancy reduces the risk of HIV transmission to the child. However, such treatment could lead to the selection of resistant virus strains in the mother. The object of this study is to check HIV+ pregnant women for resistance mutations in HIV before and after the antiretroviral therapy they receive during pregnancy. HIV-positive newborns will also be tested, to see if a resistant virus strain was transmitted from mother to child.

Conditions

  • HIV Infections

Sponsors & Collaborators

  • Hadassah Medical Organization

    lead OTHER

Principal Investigators

  • Shlomo Maayan, MD · Hadassah-Hebrew U Medical Center

  • Zehava Grossman, PhD · Central Virology Laboratory Tel HaShomer

  • Rebekah Karplus, MD · Hadassah-Hebrew U Medical Center

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-03-31
Completion
2007-12-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00197366 on ClinicalTrials.gov