Bevacizumab and Erlotinib in the Treatment of Patients With Carcinoma of Unknown Primary Site
NCT00193622 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2010-09-17
Summary
This trial will investigate the combination of bevacizumab, and erlotinib in patients with adenocarcinoma or poorly differentiated carcinoma of unknown primary site. Bevacizumab and erlotinib are relatively well-tolerated and have non-overlapping toxicity profiles. This trial will be one of the first clinical trials to evaluate a combination of targeted agents in the treatment of a solid tumor.
Conditions
- Neoplasms, Unknown Primary
Interventions
- DRUG
- DRUG
-
Erlotinib
Sponsors & Collaborators
-
Genentech, Inc.
collaborator INDUSTRY -
SCRI Development Innovations, LLC
lead OTHER
Principal Investigators
-
John D. Hainsworth, MD · SCRI Development Innovations, LLC
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-04-30
- Primary Completion
- 2005-09-30
- Completion
- 2009-01-31
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