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Effect of an Inhaled Corticosteroid on Airway Gene Expression in Asthma

NCT00187499 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL

Last updated 2008-04-03

No results posted yet for this study

Summary

The purpose of this study is to determine whether an inhaled corticosteroid (fluticasone) alters the expression of any gene expressed in the lining of the airways of asthmatics. The study uses high density gene chips which allow the study investigators to measures all gene in the human genome. We hypothesize that this approach will identify novel genes that are affected by steroids in asthmatics.

Conditions

Interventions

DRUG

Inhaled fluticasone 500 ug BID for 8 weeks

Sponsors & Collaborators

Principal Investigators

  • John V Fahy, M.D. · University of California, San Francisco

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-10-31
Completion
2005-02-28

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00187499 on ClinicalTrials.gov