Combination Drug Study of Bexarotene and Rosiglitazone to Treat CTCL
NCT00178841 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 4
Last updated 2016-02-17
Summary
The purpose of this trial is to determine if combination therapy with rosiglitazone and bexarotene might have a synergistic effect in the treatment of patients with CTCL.
Conditions
- Cutaneous T-cell Lymphoma
- Mycosis Fungoides
- Sezary Syndrome
Interventions
- DRUG
-
Rosiglitazone and Bexarotene
rosiglitazone added to bexarotene capsules
Sponsors & Collaborators
-
Vanderbilt University
lead OTHER
Principal Investigators
-
John A Zic, MD · Vanderbilt University Medical Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-06-30
- Primary Completion
- 2007-03-31
- Completion
- 2007-03-31
Countries
- United States
Study Locations
More Related Trials
-
Trial of Rituximab, Bendamustine (RB) for Patients With Follicular Lymphoma Refractory or Relapsed After Treatment With R-chemotherapy in First Line
NCT01127841 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Rituximab and Bevacizumab in Patients With Follicular Non-Hodgkin's Lymphoma
NCT00193492 ·Status: COMPLETED ·Phase: PHASE2
-
Ritlecitinib in CTCL
NCT05879458 ·Status: TERMINATED ·Phase: PHASE2
-
A Study for Participants With Relapsed Cutaneous T-Cell Lymphoma
NCT00744991 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System
NCT06385522 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Mechanism Investigation of Selinexor Combined With Lenalidomide and Rituximab in the Treatment of Diffuse Large B-cell Lymphoma
NCT05923879 ·Status: UNKNOWN
-
Lenalidomide, MTX, Ara-C and Rituximab in Relapsed Aggressive B-cell Lymphomas
NCT01788189 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Lenalidomide and Rituximab in the Treatment of Relapsed Mantle Cell Lymphoma (MCL) and Diffuse Large B-Cell Lymphoma
NCT00294632 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Long-term Use of Romidepsin in Patients With CTCL
NCT02296398 ·Status: COMPLETED
-
A Safety, Efficacy and Pharmacokinetics Study of CD11301 for the Treatment of Cutaneous T-Cell Lymphoma (CTCL)
NCT03292406 ·Status: COMPLETED ·Phase: PHASE2
-
Bendamustine and Rituximab in Combination With Copanlisib for the Treatment of Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT04155840 ·Status: TERMINATED ·Phase: PHASE2
-
Identification of Prognostic Factors and New Therapeutic Targets in Cutaneous Lymphomas
NCT04520529 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Chemotherapy for Participants With Lymphoma
NCT00436280 ·Status: COMPLETED ·Phase: PHASE2
-
Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
NCT07225439 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
A Phase II Study to Evaluate the Efficacy and Safety of F520 Combined With F007 in Patients With RR DLBCL
NCT05178836 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study to Assess the Feasibility of Romidepsin Combined With Brentuximab Vedotin in Cutaneous T-cell Lymphoma
NCT02616965 ·Status: COMPLETED ·Phase: PHASE1
-
Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma
NCT01856192 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Doxorubicin Hydrochloride Liposome and Rituximab With Combination Chemotherapy in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Burkitt-Like Lymphoma
NCT00392990 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I/II Carfilzomib Plus Lenalidomide and Rituximab in the Treatment of Relapsed/Refractory Mantle Cell Lymphoma
NCT01729104 ·Status: TERMINATED ·Phase: PHASE1
-
A Phase II Trial of Alemtuzumab and Rituximab in Patients With Previously Untreated CLL
NCT00858117 ·Status: COMPLETED ·Phase: PHASE2
-
VTX-2337 in Combination With Radiotherapy in Patients Low-Grade B-cell Lymphomas
NCT01289210 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Triamcinolone Acetonide Injections in Primary Cutaneous Lymphoma Plaques With a Novel Needle-free Drug-delivery System.
NCT05106192 ·Status: WITHDRAWN ·Phase: NA
-
Response-Adapted Therapy With Copanlisib and Rituximab in Untreated Follicular Lymphoma
NCT03789240 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Rituximab, Venetoclax, and Bortezomib for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
NCT04285268 ·Status: WITHDRAWN ·Phase: PHASE2
-
Safety and Efficacy of Bexxar Therapy in the Treatment of Relapsed/Residual B-Cell Lymphoma After Autologous Transplant
NCT00434629 ·Status: COMPLETED ·Phase: PHASE1