Improving Symptoms of Schizophrenia and Schizoaffective Disorder by Supplementing Medications With Pravastatin
NCT00177580 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 72
Last updated 2008-01-15
Summary
This study supplements patients' current medications with Pravastatin, a cholesterol-lowering medication, to try to improve residual symptoms of schizophrenia, and also to improve cognitive functioning.
Conditions
- Schizophrenia
- Schizoaffective Disorder
Interventions
- DRUG
-
Pravastatin
Sponsors & Collaborators
-
Stanley Medical Research Institute
collaborator OTHER -
University of Pittsburgh
lead OTHER
Principal Investigators
-
Jaspreet S Brar, MD, MPH · University of Pittsburgh
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-07-31
- Primary Completion
- 2007-01-31
- Completion
- 2007-07-31
Countries
- United States
Study Locations
More Related Trials
-
A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia
NCT00567203 ·Status: COMPLETED ·Phase: PHASE1
-
Effectiveness of Vitamin Supplementation in Treating People With Residual Symptoms of Schizophrenia
NCT00611806 ·Status: COMPLETED ·Phase: PHASE4
-
Simvastatin Addition for Patients With Recent-onset Schizophrenia
NCT01999309 ·Status: COMPLETED ·Phase: PHASE3
-
Pregnenolone for Cognitive and Negative Symptoms in Schizophrenia
NCT00728728 ·Status: COMPLETED ·Phase: PHASE2
-
Sulforaphane to Reduce Symptoms of Schizophrenia
NCT02810964 ·Status: COMPLETED ·Phase: PHASE2
-
Add-on Simvastatin in Schizophrenia Trial
NCT00605995 ·Status: TERMINATED ·Phase: NA
-
Effect of MMFS-202-302 on Cognitive Enhancement in Schizophrenia
NCT02237235 ·Status: COMPLETED ·Phase: PHASE2
-
Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia
NCT01242371 ·Status: COMPLETED ·Phase: NA
-
Add On Treatment for Cognitive Deficits in Schizophrenia
NCT01346163 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Of PF-03463275 As Add-On Therapy In Outpatients With Persistent Negative Symptoms Of Schizophrenia
NCT00977522 ·Status: TERMINATED ·Phase: PHASE2
-
Sodium Butyrate For Improving Cognitive Function In Schizophrenia
NCT02654405 ·Status: WITHDRAWN ·Phase: PHASE2/PHASE3
-
Pilot Study of Pregnenolone Augmentation Targeting Cognitive Symptoms in Persistently Symptomatic Patients With Schizophrenia
NCT00560937 ·Status: COMPLETED ·Phase: NA
-
Treatment of Cognitive Impairment in Men With Schizophrenia (MK5757-005)(COMPLETED)
NCT00848484 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Galantamine to Treat Schizophrenia
NCT00232349 ·Status: TERMINATED ·Phase: PHASE4
-
Proof of Concept Study of Cognitive Improvement in Patients With Schizophrenia
NCT00528905 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Trial to Examine Effects of Atomoxetine in the Treatment of Negative Symptoms in Patients With Schizophrenia
NCT00222794 ·Status: COMPLETED ·Phase: PHASE4
-
Galantamine and Memantine Combination for Cognitive Impairments in Schizophrenia
NCT02234752 ·Status: TERMINATED ·Phase: PHASE2
-
Minocycline Augmentation in Schizophrenia
NCT01561742 ·Status: UNKNOWN ·Phase: NA
-
Gamma-Amino Butyric Acid (GABA)-A Alpha2/3 Study
NCT00129441 ·Status: COMPLETED ·Phase: PHASE2
-
Brain Imaging, Cognitive Enhancement and Early Schizophrenia
NCT01561859 ·Status: COMPLETED ·Phase: NA
-
Study of a Neurocognition Enhancing Agent in Patients With Schizophrenia
NCT00894842 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia
NCT07227818 ·Status: RECRUITING ·Phase: PHASE3
-
Kuvan in People With Schizophrenia and Schizoaffective Disorder
NCT01706965 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Pregnenolone Augmentation in the Treatment of Patients With Recent-Onset Schizophrenia
NCT00847600 ·Status: COMPLETED ·Phase: PHASE4
-
Targeted Vitamin D Treatment of Schizophrenia-Associated Hyperprolinemia
NCT02197286 ·Status: WITHDRAWN ·Phase: PHASE2