Letrozole in the Treatment of Advanced or Recurrent Hormone Receptor Positive Endometrial Cancer
NCT00171808 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2016-11-18
Summary
In Western industrialized countries, endometrial cancer is the most common malignancy of the female reproductive tract.
The general therapy options are surgery, radiotherapy, chemotherapy and endocrine therapy. This trial will investigate the efficacy and safety of letrozole in the treatment of advanced or recurrent hormone receptor-positive endometrial cancer .
Conditions
Interventions
- DRUG
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmeceuticals
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-04-30
- Primary Completion
- 2010-05-31
Countries
- Germany
Study Locations
More Related Trials
-
Study of Narazaciclib (ON 123300) Plus Letrozole in Endometrial Cancer and Other Gynecologic Malignancies
NCT05705505 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of Giredestrant in Participants With Grade 1 Endometrial Cancer
NCT05634499 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma
NCT03008408 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Everolimus and Letrozole in Treating Patients With Recurrent Hormone Receptor Positive Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer
NCT02283658 ·Status: COMPLETED ·Phase: PHASE2
-
Antitumoral Activity and Safety of AEZS-108 in Women With LHRH Receptor Positive Gynecological Tumors
NCT00569257 ·Status: COMPLETED ·Phase: PHASE2
-
Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT04095364 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
BEZ235 Trial in Patients With Advanced Endometrial Carcinoma
NCT01290406 ·Status: WITHDRAWN ·Phase: PHASE2
-
Aminopterin in Treating Patients With Recurrent or Refractory Endometrial Cancer
NCT00003821 ·Status: WITHDRAWN ·Phase: PHASE2
-
Erlotinib in Treating Patients With Locally Advanced and/or Metastatic Endometrial Cancer
NCT00030485 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer
NCT04486352 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Gemcitabine in Treating Patients With Recurrent or Refractory Cancer of the Uterus
NCT00003316 ·Status: TERMINATED ·Phase: PHASE2
-
Patients Characteristics, Treatment Pattern & Outcomes of Patients With Advanced, Recurrent or Metastatic Endometrial Carcinoma
NCT05364905 ·Status: COMPLETED
-
Abemaciclib and Letrozole in Patients With Estrogen Receptor-positive Rare Ovarian Cancer
NCT05872204 ·Status: RECRUITING ·Phase: PHASE2
-
Exemestane in Advanced and Recurrent Endometrial Carcinoma
NCT01965080 ·Status: COMPLETED ·Phase: PHASE2
-
Abemaciclib and Letrozole to Treat Endometrial Cancer
NCT04393285 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Abemaciclib and Letrozole in Treating Patients With Endometrial Cancer
NCT04049227 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
BKM120 as Second-line Therapy for Advanced Endometrial Cancer
NCT01289041 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma
NCT05603910 ·Status: RECRUITING ·Phase: PHASE1
-
Ribociclib and Letrozole in Treating Patients With Relapsed ER Positive Ovarian, Fallopian Tube, Primary Peritoneal, or Endometrial Cancer
NCT02657928 ·Status: COMPLETED ·Phase: PHASE2
-
GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients
NCT05316935 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
AP23573 in Female Adult Patients With Recurrent or Persistent Endometrial Cancer (8669-019)(COMPLETED)
NCT00122343 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer
NCT06394804 ·Status: RECRUITING ·Phase: PHASE2
-
Paclitaxel in Treating Patients With Refractory or Recurrent Endometrial Cancer
NCT00022620 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer
NCT05691010 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial Cancers
NCT00703807 ·Status: COMPLETED ·Phase: PHASE1