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Standard vs. Reduced-Intensity Conditioning in Patients With Acute Myeloid Leukemia in First Remission

NCT00150878 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 198

Last updated 2013-06-20

No results posted yet for this study

Summary

The primary goal of the study is to show that the treatment-related mortality of allogeneic hematopoietic stem cell transplantation an be significantly reduced by using a combination of 8 Gy total-body-irradiation and fludarabine in comparison to the conventional combination of 12 Gy TBI and 120 mg/kg Cyclophosphamide.

Conditions

Interventions

OTHER

Conditioning therapy

Preparation before allogeneic transplantation

Sponsors & Collaborators

  • University Hospital Carl Gustav Carus

    lead OTHER

Principal Investigators

  • Gerhard Ehninger, MD · Director of Med. Klink und Poliklinik I, Technical University Dresden

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-12-31
Primary Completion
2009-12-31
Completion
2010-12-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00150878 on ClinicalTrials.gov