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Genetic Study of Nephrolithiasis in Gouty Diathesis

NCT00149305 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 37

Last updated 2023-04-04

No results posted yet for this study

Summary

Gouty diathesis describes uric acid or calcium oxalate nephrolithiasis and low urinary pH (\<5.5). A hereditary component has been outlined for several forms of nephrolithiasis (such as hypercalciuria, hyperoxaluria, cystinuria, renal tubular acidosis), leading to the hypothesis of a genetic predisposition to nephrolithiasis. At the Unit of Nephrology, Ospedali Riuniti di Bergamo, more than 100 patients affected by gouty diathesis are followed. Fifty percent of them has a familiarity for kidney stones formation. The aim of our study is to identify the genetic factors that predispose to the development of nephrolithiasis in patients with gouty diathesis.

Conditions

  • Nephrolithiasis

Interventions

OTHER

Genetic analyses

OTHER

Genetic analyses

Sponsors & Collaborators

  • Mario Negri Institute for Pharmacological Research

    lead OTHER

Principal Investigators

  • Erica Daina, MD · Mario Negri Institute

Eligibility

Min Age
10 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-05-31
Primary Completion
2010-01-31
Completion
2010-05-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00149305 on ClinicalTrials.gov