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Heparin Management During Cardiopulmonary Bypass in Children

NCT00146653 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2013-11-20

No results posted yet for this study

Summary

We propose a comparison between between our standard ACT based heparin management protocol for children undergoing CPB and a patient-specific heparin concentration-based heparin management protocol. We hypothesize that a heparin concentration-based anticoagulation management protocol during CPB in children will result in more effective attenuation of hemostatic activation as reflected by decreased levels of thrombin formation and, ultimately, better preservation of hemostasis postoperatively.

An additional 20 patients will be enrolled to address the validation of heparin concentrations calculated by the Hepcon machine with laboratory-measured heparin concentrations. These patients will not be randomized and therefore will not receive an intervention.

Conditions

  • Primary Condition: Heart Defects Requiring Surgery With CPB

Sponsors & Collaborators

  • Emory University

    lead OTHER

Principal Investigators

  • Nina A Guzzetta, MD · Emory University

Eligibility

Max Age
6 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-12-31
Primary Completion
2010-01-31
Completion
2010-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00146653 on ClinicalTrials.gov