Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Related Stem Cell Transplantation
NCT00144703 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 55
Last updated 2012-01-26
Summary
The purpose of this study is to evaluate the ability of sirolimus to prevent graft versus host disease (GVHD) in patients following stem cell transplant from a related donor.
Conditions
- Hematologic Malignancies
- Myelogenous Leukemia
- Acute Lymphoblastic Leukemia
- Myelodysplastic Syndrome
- Non-Hodgkin's Lymphoma
- Hodgkin's Disease
Interventions
- DRUG
-
Sirolimus
- DRUG
Sponsors & Collaborators
-
Brigham and Women's Hospital
collaborator OTHER - lead OTHER
Principal Investigators
-
Corey Cutler, MD, MPH · Dana-Farber Cancer Institute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-07-31
- Primary Completion
- 2006-11-30
- Completion
- 2006-11-30
Countries
- United States
Study Locations
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