Comparison of Treatment Simplification by LPV/r vs Current Treatment Continuation in HIV-Infected Patients
NCT00140751 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 186
Last updated 2013-09-19
Summary
The purpose of this study is to compare the efficacy and tolerance of a treatment simplification by a Lopinavir/ritonavir monotherapy versus continuation of current treatment in HIV-infected patients
Conditions
- HIV Infections
Interventions
- DRUG
-
Lopinavir/ritonavir (drug)
Sponsors & Collaborators
- collaborator INDUSTRY
-
Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
lead OTHER
Principal Investigators
-
Jean-Luc MEYNARD, MD, PhD · Hôpital Saint-Antoine - Service des Maladies Infectieuses et Tropicales (Paris, France)
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-10-31
- Primary Completion
- 2008-01-31
- Completion
- 2008-01-31
Countries
- France
Study Locations
More Related Trials
-
Pilot Simplification Study to Lopinavir/Ritonavir 800/200 mg Monotherapy Regimen Once Daily
NCT01581853 ·Status: COMPLETED ·Phase: PHASE4
-
Treatment of HIV/HCV Coinfection With Peg-IFN and Ribavirin in Patients Receiving ART Monotherapy With Lopinavir/r
NCT00866021 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate the Activity and Tolerability of Lopinavir/Ritonavir and Lamivudine Bitherapy in HIV Patients With Viral Suppression
NCT01471821 ·Status: COMPLETED ·Phase: PHASE4
-
High Dose Ritonavir/Lopinavir Liquid Formulation in Salvage Therapy for Protease Inhibitor Resistant HIV Disease
NCT00247143 ·Status: UNKNOWN ·Phase: NA
-
Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success With Protease Inhibitor-Containing HAART Regimen(s)
NCT00028301 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical, Virological and Safety Outcomes of a Lopinavir/Ritonavir-Based Regimen in HIV-1 Infected Patients in Routine Clinical Use in China
NCT01074931 ·Status: COMPLETED
-
Prevention of Lipoatrophy in Patients Treated With Lopinavir/Ritonavir in Monotherapy Versus ZDV + 3TC + ABC
NCT00865475 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Kaletra Monotheraphy Compared to Kaletra Based Triple Therapy to Treat HIV in Antiretroviral Naїve Patients
NCT00234923 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Lopinavir/Ritonavir Tablets Comparing Once-Daily Versus Twice-Daily Administration When Coadministered With Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Antiretroviral-Experienced Human Immunodeficiency Virus Type 1 Infected Subjects
NCT00358917 ·Status: COMPLETED ·Phase: PHASE3
-
Safety of Lopinavir/Ritonavir (Kaletra) in HIV/HCV Co-infected Subjects vs Baseline Liver Biopsy Metavir Score
NCT00234975 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Two Different Doses of ABT-378/Ritonavir in HIV-Infected Patients Who Have Taken Protease Inhibitors and Non-Nucleoside Reverse Transcriptase Inhibitors
NCT00038636 ·Status: COMPLETED ·Phase: PHASE3
-
Simplification to Atazanavir/Ritonavir + Lamivudine as Maintenance Therapy
NCT01307488 ·Status: COMPLETED ·Phase: PHASE4
-
A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen
NCT00931463 ·Status: COMPLETED ·Phase: PHASE4
-
A Multicenter Study to Assess the Tolerability of Once Daily Lopinavir/Ritonavir (LPV/r) Liquid Versus Capsules
NCT00281606 ·Status: COMPLETED ·Phase: PHASE4
-
Comparing Standard-Dose Versus Adjusted-Dose Lopinavir/Ritonavir Therapy in HIV-Infected Persons With Drug Resistance
NCT00046033 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate Darunavir/Ritonavir + Lamivudine Versus Continuing With Darunavir/Ritonavir + Tenofovir/Emtricitabine or Abacavir/Lamivudine in HIV Infected Subject
NCT02159599 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological Failure
NCT00025727 ·Status: UNKNOWN ·Phase: PHASE3
-
A Comparison of Adherence Rates to Ritonavir and Its Accompanying Protease Inhibitor
NCT00432783 ·Status: COMPLETED
-
Clinical Study to Evaluate the Efficacy and Safety of Lopinavir/Ritonavir Monotherapy Versus Darunavir/Ritonavir Monotherapies as Simplification Switching Strategies of PI/NNRTI-Triple Therapy Based-Regimens
NCT00994344 ·Status: COMPLETED ·Phase: PHASE4
-
Induction-maintenance of Lopinavir/r in HIV-infected Subjects
NCT00159224 ·Status: COMPLETED ·Phase: PHASE4
-
Maintenance Boosted Lopinavir Monotherapy Following Salvage Protease-inhibitor (PI) Based Regimen in HIV With Non-nucleoside Reverse Transcriptase Inhibitors (NNRTI) Based Regimen Failure
NCT01189695 ·Status: COMPLETED ·Phase: PHASE4
-
Lopinavir/Ritonavir Monotherapy Versus Standard Highly Active Antiretroviral Therapy (HAART) in HIV/HCV Coinfected Patients Starting Treatment With Anti-Hepatitis C Virus (HCV) Therapy
NCT00437684 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study to Assess Effectiveness and Safety of Fixed Dose Combination of Lopinavir/Ritonavir (LPV/r) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Patients After Switching From Kaletra in the Routine Clinical Settings of Russian Federation
NCT04138199 ·Status: TERMINATED
-
Amprenavir/Ritonavir, Saquinavir/Ritonavir or Efavirenz in HIV-Infected Subjects Following Failure With Kaletra (ABT-378/Ritonavir) as Their First Protease Inhibitor Based HAART
NCT00038532 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Lopinavir/Ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice Daily Administration, When Coadministered With Nucleoside Reverse Transcriptase Inhibitors in Antiretroviral Naive Human Immunodeficiency Virus Type 1 Infected Subjects
NCT00262522 ·Status: COMPLETED ·Phase: PHASE3