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Treatment of Acute Schizophrenia With Vitamin Therapy

NCT00140166 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2009-11-25

No results posted yet for this study

Summary

Controlled studies using the orthomolecular approach have been few (Deutsch, Ananth, \& Ban, 1977). Those that were done were performed in chronic schizophrenia or in populations that included bipolar and schizoaffective patients. Both of these diagnostic groups are not today considered to benefit from the orthomolecular approach. Moreover, some negative studies of high-dose niacin were done in patients who were not otherwise given general counseling for good diet as described above. Therefore, this proposal is to study in a controlled manner carefully defined first onset schizophrenic patients using the protocol advocated by Osmond and Hoffer (1962). Patients can enter the study if they have been ill less than 1 year and are in their first hospitalization.

Conditions

  • Acute Schizophrenia

Interventions

DRUG

niacinamide

DRUG

pyridoxine

DRUG

ascorbate

Sponsors & Collaborators

  • Supported by a Hilton Family Foundation grant to

    collaborator UNKNOWN

  • International Schizophrenia Foundation

    collaborator UNKNOWN

  • Beersheva Mental Health Center

    lead OTHER_GOV

Principal Investigators

  • Vladimir Lerner, MD · Beersheva Mental Health Center

  • RH Belmaker, MD · Ben-Gurion University of the Negev

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-07-31
Completion
2008-05-31

Countries

  • Israel

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00140166 on ClinicalTrials.gov