Bevacizumab in Combination With Temozolomide in Patients With Neuroendocrine Tumors
NCT00137774 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 34
Last updated 2013-04-09
Summary
The purpose of this study is to determine what effects (good and bad) bevacizumab and temozolomide have on patients with neuroendocrine tumors.
Conditions
Interventions
- DRUG
-
Given intravenously every other week. Participants can continue to receive study drug as long as there is no disease progression or serious side effects.
- DRUG
-
Given once daily for one week followed by a one week rest period. This one-week on/one-week off scheduled will be continued as long as there is no disease progression or serious side effects.
Sponsors & Collaborators
-
Massachusetts General Hospital
collaborator OTHER -
Beth Israel Deaconess Medical Center
collaborator OTHER -
Brigham and Women's Hospital
collaborator OTHER -
Genentech, Inc.
collaborator INDUSTRY -
Schering-Plough
collaborator INDUSTRY - lead OTHER
Principal Investigators
-
Matthew H. Kulke, MD · Dana-Farber Cancer Institute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-11-30
- Primary Completion
- 2005-07-31
- Completion
- 2012-12-31
Countries
- United States
Study Locations
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