Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit
NCT00131521 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 260
Last updated 2009-06-23
Summary
This study compares N-acetylcysteine (mucomyst) and sodium chloride to determine their efficacy in the prevention of pulmonary mucus obstruction and retention in intubated patients admitted to the surgical trauma intensive care unit (STICU).
Conditions
- Mucus Obstruction
- Intubation
Interventions
- DRUG
-
mucomyst
- DRUG
-
sodium chloride (saline)
Sponsors & Collaborators
-
The University of Texas Health Science Center at San Antonio
lead OTHER
Principal Investigators
-
John G. Myers, M.D. · University of Texas Health Science Center San Antonio
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-01-31
- Completion
- 2007-12-31
Countries
- United States
Study Locations
More Related Trials
-
Early Tracheotomy Versus Prolonged Endotracheal Intubation in Intensive Care Unit (ICU) Patients
NCT00127621 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy of Mechanical Ventilation With Facial Mask to Reduce Gastric Insufflation
NCT01652924 ·Status: UNKNOWN ·Phase: NA
-
Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
NCT07308171 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Impact of Prophylactic High Flow Nasal Oxygen in Post-Operative Thoracic Surgical Patients
NCT03024112 ·Status: COMPLETED ·Phase: NA
-
Intubation and Extubation Over 48 Hours Mechanical Ventilation
NCT01123681 ·Status: UNKNOWN
-
Comparison for the Effect of Neuromuscular Blocking Agents Versus Sedation Alone on Severe ARDS Patients Due to COVID-19
NCT04922814 ·Status: COMPLETED ·Phase: NA
-
The Effects of Mechanical Insufflation-exsufflation on Airway Mucus Clearance in the ICU
NCT03178565 ·Status: UNKNOWN ·Phase: NA
-
Effectiveness and Safety of Respiratory Training in the Prevention and Severity of COVID-19
NCT04326114 ·Status: UNKNOWN ·Phase: NA
-
Pre-oxygenation With High-flow Nasal Cannula in Adults During Rapid Sequence Induction Anesthesia
NCT03516175 ·Status: COMPLETED ·Phase: NA
-
Evaluation of a Closed Suction System to Remove Secretions From the Endotracheal Tube
NCT01912105 ·Status: COMPLETED ·Phase: PHASE2
-
Fraction of Inspired Oxygen and Atelectasis in Children
NCT02870842 ·Status: COMPLETED ·Phase: NA
-
Direct Topical Lung T3 Treatment to Improve Outcome & Sequelae of COVID-19 Acute Respiratory Distress Syndrome
NCT04725110 ·Status: WITHDRAWN ·Phase: PHASE2
-
Prevention of Broncho-aspiration (BA) in Adult Subjects During Their ICU Stay
NCT05284084 ·Status: COMPLETED ·Phase: NA
-
High Flow Nasal Oxygenation Versus Non-invasive Ventilation for Patients With Blunt Chest Trauma
NCT05342103 ·Status: COMPLETED ·Phase: NA
-
Pragmatic Trial Examining Oxygenation Prior to Intubation
NCT05267652 ·Status: COMPLETED ·Phase: NA
-
Subglottic Secretion Culture in Predicting Tracheal Microbial Flora
NCT03153241 ·Status: COMPLETED
-
Early Percutaneous Tracheostomy for Cardiac Surgery (ETOC)
NCT00347321 ·Status: COMPLETED ·Phase: PHASE3
-
The Effects of Endotracheal Suctioning on Pain and Serum Markers
NCT06692400 ·Status: RECRUITING ·Phase: NA
-
High-flow Nasal Oxygen Therapy to Prevent Extubation Failure in Adult Trauma Intensive Care Patients
NCT06110390 ·Status: RECRUITING ·Phase: NA
-
Automated Secretion Removal in ICU Patients
NCT05056103 ·Status: TERMINATED ·Phase: NA
-
Airway Clearance in Bronchiectasis: is Non-Invasive Ventilation a Useful Adjunct in Moderate to Severe Disease?
NCT00522314 ·Status: COMPLETED ·Phase: NA
-
Double-blind, Randomized, Controlled Clinical Trial to Assess Efficacy of MSC in Patients With COVID-19 ARDS
NCT04615429 ·Status: COMPLETED ·Phase: PHASE2
-
Apneic Oxygenation With a Nasal Cannula in the Obese and Morbidly Obese Surgical Patient
NCT03671837 ·Status: COMPLETED ·Phase: NA
-
Assessment of the Efficacy of Tracheal Oxygen Administration During Bronchoscopy - a Phase II Trial
NCT01786642 ·Status: UNKNOWN
-
MultiStem Administration for COVID-19 Induced ARDS (MACoVIA)
NCT04367077 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3