Evaluation of GW406381 in Treating Adults With Osteoarthritis Of The Knee
NCT00120900 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1340
Last updated 2017-01-19
Summary
This study was designed to evaluate the effectiveness of GW406381 (a COX-2 inhibitor) in treating the signs and symptoms of osteoarthritis of the knee.
Conditions
- Osteoarthritis, Knee
Interventions
- DRUG
-
GW406381
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials · GlaxoSmithKline
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-05-31
- Primary Completion
- 2007-09-30
- Completion
- 2007-09-30
Countries
- Denmark
- Netherlands
- Norway
- South Korea
- Spain
- Sweden
Study Locations
More Related Trials
-
Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the Knee
NCT00652808 ·Status: COMPLETED ·Phase: PHASE3
-
A Dose-Ranging Study Of Valdecoxib 5 Mg, 10 Mg, And 20 Mg Once Daily Versus Placebo In Patients With Osteoarthritis Of The Knee (Japan)
NCT00650624 ·Status: COMPLETED ·Phase: PHASE2
-
A Proof-of-concept Study to Examine QUC398 in Participants With Knee OA
NCT05462990 ·Status: TERMINATED ·Phase: PHASE2
-
Assessment of Protective Effect of JOINS on Cartilage in Knee Osteoarthritis
NCT01293955 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis (0686-006)
NCT00296569 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability and Preliminary Efficacy of Multiple Intra-articular Injections of LRX712 in Patients With Knee OA
NCT04097379 ·Status: COMPLETED ·Phase: PHASE2
-
Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part II
NCT01598415 ·Status: COMPLETED ·Phase: PHASE2
-
A Study With GLPG1972 in Osteoarthritis Subjects
NCT03311009 ·Status: COMPLETED ·Phase: PHASE1
-
Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients With Painful Osteoarthritis of the Knee
NCT02845271 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Bone Health Study of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis
NCT03727022 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis
NCT04886258 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Lumiracoxib in Patients With Knee Osteoarthritis (OA).
NCT00366938 ·Status: COMPLETED ·Phase: PHASE3
-
Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
NCT00689273 ·Status: COMPLETED ·Phase: PHASE2
-
A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study
NCT03936192 ·Status: WITHDRAWN ·Phase: PHASE3
-
Efficacy and Safety of Lumiracoxib in Patients With Primary Knee Osteoarthritis(OA)
NCT00475800 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase II Study Looking at Moderate to Severe Osteoarthritis Knee Pain
NCT00394563 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability and Pharmacokinetics of Intraarticular 4P004 Single Dose in Patient With KL 2-4 Osteoarthritic Knee
NCT05419856 ·Status: COMPLETED ·Phase: PHASE1
-
A 12 Week, Phase II Trial to Evaluate the Efficacy and Safety of WIN-34B in Patients With Osteoarthritis of the Knee
NCT01873053 ·Status: COMPLETED ·Phase: PHASE2
-
Safety of Single Doses of SAR113945 and Efficacy and Safety of a New Formulation Given Into the Knee in Osteoarthritis Patients / Part I
NCT01463488 ·Status: COMPLETED ·Phase: PHASE1
-
A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee.
NCT02604381 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Lumiracoxib in Patients With Primary Knee Osteoarthritis (OA)
NCT00367315 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of SKCPT in Patients With Knee Osteoarthritis: Phase III Clinical Trial
NCT05930080 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of a New Formulation of Chondroitin Sulfate and Glucosamine Sulfate to Treat Knee Osteoarthritis
NCT01893905 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate Safety and Tolerability of MIV-711 in Osteoarthritis Patients
NCT03037489 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Lumiracoxib
NCT00267215 ·Status: COMPLETED ·Phase: PHASE3