Trial to Reduce Antimicrobial Prophylaxis Errors (TRAPE)

Summary

The specific aims are to determine the incidence of medication errors related to antimicrobial prophylaxis for cardiovascular surgery, joint replacement surgery, and hysterectomies across a heterogeneous sample of hospitals; identify organizational and practitioner factors associated with error rates, and evaluate the effectiveness of a multifaceted intervention in reducing prophylaxis error rates compared to written feedback alone in a sample of 44 hospitals enrolled in the study using a rigorous group-randomized design.

Conditions

• Cardiovascular Surgical Procedures
• Arthroplasty, Replacement
• Hysterectomy

Interventions

BEHAVIORAL

Quality improvement strategies

Sponsors & Collaborators

• Joint Commission on Accreditation of Healthcare Organizations

  collaborator OTHER

• Society for Healthcare Epidemiology of America

  collaborator OTHER

• Centers for Disease Control and Prevention

  collaborator FED

• Agency for Healthcare Research and Quality (AHRQ)

  lead FED

Principal Investigators

• Stephen B. Krichevsky, PhD · Wake Forest University Health Sciences

• Barbara I. Braun, PhD · Joint Commission on Accreditation of Healthcare Organizations

• Edward Wong, MD · VA Office of Research and Development

• Steve Solomon, MD · Centers for Disease Control and Prevention

• Bryan Simmons, MD · Methodist Health System

• Andrew J. Bush, PhD · University of Tennessee

• John Burke, MD · LDS Hospital

• Michele R. Bozikis, MPH · Joint Commission on Accreditation of Healthcare Organizations

• Linda Kusek, MPH · Joint Commission on Accreditation of Healthcare Organizations

Study Design

Allocation

RANDOMIZED

Purpose

ECT

Masking

NONE

Model

PARALLEL

Eligibility

Sex

Healthy Volunteers

No

Timeline & Regulatory

Start

2002-08-31

Completion

2005-12-31

Countries

• United States

Study Locations