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AVONEX® Combination Trial - "ACT"

NCT00112034 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 350

Last updated 2008-05-09

No results posted yet for this study

Summary

The purpose of this study is to determine the efficacy and safety of combination therapy with AVONEX plus low dose oral methotrexate (MTX), every other month courses of intravenous methylprednisolone (IVMP), or both in patients with continued disease activity on AVONEX monotherapy.

Conditions

  • Multiple Sclerosis, Relapsing-Remitting

Interventions

DRUG

Methotrexate

DRUG

IV methylprednisolone

Sponsors & Collaborators

Principal Investigators

  • Jeffrey A. Cohen, MD · The Cleveland Clinic

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-06-30
Primary Completion
2006-06-30
Completion
2007-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00112034 on ClinicalTrials.gov