The HERO-study: Effects of Roflumilast in Patients With COPD (Chronic Obstructive Pulmonary Disease) (BY217/M2-121)

Effect of Roflumilast at Acute Exacerbations of Chronic Obstructive Pulmonary Disease

NCT01473758 ·Status: TERMINATED ·Phase: PHASE2

Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Combinations of Long-acting β2-agonists (LABA) and Inhaled Glucocorticosteroid (ICS)

NCT01329029 ·Status: COMPLETED ·Phase: PHASE4

Evaluation of Tolerability and Pharmacokinetics of Roflumilast, 250μg and 500μg, as add-on to Standard COPD Treatment to Treat Severe COPD

NCT02165826 ·Status: COMPLETED ·Phase: PHASE3

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The AURA Study (BY217/M2-124)

NCT00297102 ·Status: COMPLETED ·Phase: PHASE3

Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)

NCT01443845 ·Status: COMPLETED ·Phase: PHASE4

Long-term Observational Study of the Safety of Roflumilast

NCT03381573 ·Status: COMPLETED

A Chronic Obstructive Pulmonary Disease (COPD) Trial Investigating Roflumilast on Safety and Effectiveness in China, Hong Kong and Singapore:

NCT01313494 ·Status: COMPLETED ·Phase: PHASE3

The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis

NCT03073798 ·Status: COMPLETED ·Phase: PHASE4

OPUS Study: Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (BY217/M2-111)

NCT00076089 ·Status: COMPLETED ·Phase: PHASE3

Long-term Study of Safety and Efficacy of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-08)

NCT00246935 ·Status: COMPLETED ·Phase: PHASE3

Efficacy and Safety of Oral Roflumilast Taken Once Daily in Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (BY217/M2-119)

NCT00242320 ·Status: COMPLETED ·Phase: PHASE3

Efficacy and Safety of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-06)

NCT00242294 ·Status: COMPLETED ·Phase: PHASE2/PHASE3

Effect of Roflumilast on Lung Function in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Salmeterol: The EOS Study (BY217/M2-127)

NCT00313209 ·Status: COMPLETED ·Phase: PHASE3

Roflumilast Safety Administered Once a Day on Alternate Days for Two Weeks Compared to the Usual Dosage Once Daily

NCT01849341 ·Status: COMPLETED ·Phase: PHASE4

Pharmacokinetic Study of Single and Repeated Dose of Roflumilast 500 µg , in Healthy Chinese Subjects

NCT01354782 ·Status: COMPLETED ·Phase: PHASE1

Effects of Roflumilast in Hospitalized Chronic Obstructive Pulmonary Disease( COPD) on Mortality and Re-hospitalization

NCT01973998 ·Status: COMPLETED ·Phase: PHASE3

A Multi-center Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of R7103 Following Repeated Inhalation in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease

NCT01009424 ·Status: WITHDRAWN ·Phase: PHASE1

Effects of ROFLUMILAST on Subclinical Atherosclerosis in Chronic Obstructive Pulmonary Disease (COPD)

NCT01630200 ·Status: COMPLETED ·Phase: PHASE4

BI 113608 Administered as Tablets Twice Daily Over 4 Weeks in Patients With Chronic Obstructive Pulmonary Disease Associated With Chronic Bronchitis

NCT01958008 ·Status: COMPLETED ·Phase: PHASE1

Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871

NCT02971293 ·Status: COMPLETED ·Phase: PHASE2

Effect of Roflumilast on Airway Blood Flow as an Expression of Airway Inflammation in COPD

NCT02097992 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Evaluation of Clinical Effectiveness of Roflumilast in Routine Practice, in Chronic Obstructive Pulmonary Disease (COPD) Patients in Greece

NCT02187926 ·Status: COMPLETED

Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease

NCT01595750 ·Status: UNKNOWN ·Phase: PHASE4

Effect of Roflumilast on Quality of Life, Lung Function and Mucus Properties in Patients With Bronchiectasis

NCT03988816 ·Status: UNKNOWN ·Phase: PHASE2

A Single-dose Study to Investigate the Effects of 3 Different Doses of Inhaled AZD2115 in COPD Patients

NCT01498081 ·Status: COMPLETED ·Phase: PHASE2