Treatment of HER2-Positive Metastatic Breast Cancer With Herceptin and Bevacizumab (Antibodies Against HER2 and VEGF)
NCT00095706 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2015-09-25
Summary
The purpose of this study is to evaluate the safety and effectiveness of combined treatment with trastuzumab (Herceptin) and bevacizumab (anti-VEGF antibody) in patients with HER2-positive metastatic breast cancer.
Conditions
Interventions
- DRUG
-
Bevacizumab (drug), Herceptin (drug)
Sponsors & Collaborators
-
Genentech, Inc.
collaborator INDUSTRY -
Translational Oncology Research International
lead OTHER
Principal Investigators
-
Mark D Pegram, MD · University of California, Los Angeles
-
Fairooz Kabbinavar, MD · Chief Medical Officer, TORI
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-06-30
- Primary Completion
- 2007-04-30
- Completion
- 2012-01-31
Countries
- United States
Study Locations
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