PANVAC™-VF Vaccine for the Treatment of Metastatic Pancreatic Cancer After Failing a Gemcitabine-Containing Regimen
NCT00088660 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 250
Last updated 2006-02-08
Summary
The objectives of this multi-center, randomized, controlled trial are to evaluate the safety and efficacy of PANVAC-VF in combination with Granulocyte-macrophage colony-stimulating factor (GM-CSF) versus best supportive care or palliative chemotherapy.
Conditions
Interventions
- BIOLOGICAL
-
PANVAC™-VF
Sponsors & Collaborators
-
Therion Biologics Corporation
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-06-30
Countries
- United States
Study Locations
More Related Trials
-
Safety and Efficacy of Combination Listeria/GVAX Immunotherapy in Pancreatic Cancer
NCT01417000 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy and Sargramostim in Treating Patients With Pancreas Cancer That Cannot Be Removed By Surgery
NCT00669734 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Vaccine Therapy Combined With Adjuvant Chemoradiotherapy in Treating Patients With Resected Stage I or Stage II Adenocarcinoma (Cancer) of the Pancreas
NCT00084383 ·Status: COMPLETED ·Phase: PHASE2
-
Pancreatic Tumor Cell Vaccine (GVAX), Cyclophosphamide, SBRT, and FOLFIRINOX in Patients With Resected Adenocarcinoma of the Pancreas
NCT01595321 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
NCT00088894 ·Status: COMPLETED ·Phase: PHASE3
-
Vaccine Therapy in Treating Patients With Stage I or Stage II Pancreatic Cancer
NCT00003025 ·Status: COMPLETED ·Phase: PHASE1
-
GVAX Pancreas Vaccine (With CY) and CRS-207 With or Without Nivolumab
NCT02243371 ·Status: COMPLETED ·Phase: PHASE2
-
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread
NCT04233866 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Vaccine Therapy With or Without Cyclophosphamide in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Stage I or Stage II Pancreatic Cancer That Can Be Removed by Surgery
NCT00727441 ·Status: COMPLETED ·Phase: PHASE2
-
Cvac as Maintenance Treatment Patients With Resected Stage I or Stage II Adenocarcinoma (Cancer) of the Pancreas
NCT02310971 ·Status: WITHDRAWN ·Phase: PHASE2
-
Gemcitabine and Capecitabine With or Without Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
NCT00425360 ·Status: COMPLETED ·Phase: PHASE3
-
Personalized Tumor Neoantigen MRNA Therapy Adjuvant Treatment for Postoperative Pancreatic Cancer.
NCT06888674 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer (Phase1/2)
NCT00655785 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
NCT04665947 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Study of MM-398 With or Without 5-FU/LV, Versus 5-FU/LV in Patients With Metastatic Pancreatic Cancer
NCT01494506 ·Status: COMPLETED ·Phase: PHASE3
-
Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Patients With Peritoneal Metastasis From Pancreatic Adenocarcinoma
NCT07253662 ·Status: RECRUITING ·Phase: PHASE1
-
GV1001 and Gemcitabine in Sequential Combination to Gemcitabine Monotherapy in Pancreatic Cancer
NCT00358566 ·Status: TERMINATED ·Phase: PHASE3
-
A Randomized Phase 2/3 Multi-Center Study of SM-88 in Participants With Metastatic Pancreatic Cancer
NCT03512756 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
Bevacizumab, Gemcitabine, and Oxaliplatin in Treating Patients With Metastatic Pancreatic Cancer
NCT00112528 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine, Infusional 5 Fluorouracil and Bevacizumab in Patients With Advanced Pancreas Cancer
NCT00417976 ·Status: COMPLETED ·Phase: PHASE2
-
HLA-A*0201 Restricted Peptide Vaccine Therapy With Gemcitabine With Gemcitabine in Patient Pancreatic Cancer (Phase1)
NCT01266720 ·Status: UNKNOWN ·Phase: PHASE1
-
Study of Weekly Genexol®-PM Plus Gemcitabine in Subjects With Recurrent and Metastatic Adenocarcinoma of the Pancreas
NCT02739633 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase 2, Nab Paclitaxel/Gemcitabine Alone and in Combination With ACP-196 in Subjects With Metastatic Pancreatic Cancer
NCT02570711 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Personalized Tumor Vaccines (PCVs) and a PD-L1 Blocker in Patients With Pancreatic Cancer That Can be Treated With Surgery
NCT04161755 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Resected or Locally Advanced Unresectable Pancreatic Cancer
NCT00008099 ·Status: COMPLETED ·Phase: PHASE1