Safety and Efficacy of Atiprimod for Patients With Refractory Multiple Myeloma
NCT00086216 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2007-12-21
Summary
This is a Phase I/IIa clinical trial to identify the maximum tolerated dose of atiprimod and to evaluate the safety of atiprimod in patients with refractory or relapsed multiple myeloma.
Conditions
Interventions
- DRUG
-
Atiprimod
Oral, once a day, 14 days on 14 days off
Sponsors & Collaborators
-
Callisto Pharmaceuticals
lead INDUSTRY
Principal Investigators
-
Gary Jacob, PhD · Callisto Pharmaceuticals
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-05-31
- Completion
- 2007-11-30
Countries
- United States
Study Locations
More Related Trials
-
An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma
NCT02211014 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of Romidepsin and Bortezomib for Multiple Myeloma
NCT00765102 ·Status: TERMINATED ·Phase: PHASE2
-
Safety and Dose Determining Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma
NCT00723359 ·Status: COMPLETED ·Phase: PHASE1
-
Nivolumab in Multiple Myeloma Patients After Idecabtagene Vicleucel
NCT06523621 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma
NCT00530816 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of QLS32015 in Patients With Recurrent or Refractory Multiple Myeloma
NCT05920876 ·Status: UNKNOWN ·Phase: PHASE1
-
AZD6244 (Selumetinib) in Treating Patients With Multiple Myeloma
NCT01085214 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of AT7519M Alone and AT7519M Plus Bortezomib in Patients With Previously Treated Multiple Myeloma
NCT01183949 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of Bortezomib and Dexamethasone With or Without Cyclophosphamide in Patients With Relapsed or Not Controllable Multiple Myeloma
NCT00813150 ·Status: COMPLETED ·Phase: PHASE3
-
S1211 Bortezomib, Dexamethasone, and Lenalidomide With or Without Elotuzumab in Treating Patients With Newly Diagnosed High-Risk Multiple Myeloma
NCT01668719 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Panobinostat and Carfilzomib in Treating Participants With Relapsed or Refractory Multiple Myeloma
NCT01301807 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma
NCT00594126 ·Status: COMPLETED ·Phase: PHASE1
-
Determining the Feasibility of MLN9708 as Maintenance After Allogeneic Stem Cell Transplant for Multiple Myeloma
NCT02168101 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of bb2121 Versus Standard Regimens in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM)
NCT03651128 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Rituximab and Cyclophosphamide in Treating Patients With High Risk, Refractory, or Relapsed Multiple Myeloma
NCT00258206 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
NCT06232707 ·Status: WITHDRAWN ·Phase: PHASE3
-
A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Patients With Relapse or Refractory Multiple Myeloma
NCT01470131 ·Status: TERMINATED ·Phase: PHASE3
-
A Study of QLS4131 in Patients With Recurrent or Refractory Multiple Myeloma
NCT06500507 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma
NCT06106945 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Melphalan, Total Marrow Irradiation, and Autologous Stem Cell Transplantation in Treating Patients With High-Risk Multiple Myeloma
NCT03100877 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Trial for Patients Not Qualifying for TT4 and TT5 Protocols Because of Prior Therapy
NCT00871013 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study on the Safety, Anti-tumor Activity and Pharmacology of IPH2101 Combined With Lenalidomide in Patients With Multiple Myeloma Experiencing a First or Second Relapse
NCT01217203 ·Status: COMPLETED ·Phase: PHASE1
-
An Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma and in Subjects With High-Risk Multiple Myeloma
NCT03601078 ·Status: COMPLETED ·Phase: PHASE2
-
Abatacept, Ixazomib Citrate, and Dexamethasone in Treating Patients With Multiple Myeloma Resistant to Chemotherapy
NCT03457142 ·Status: TERMINATED ·Phase: PHASE2
-
A Study Assessing the Health-Related Quality of Life (HRQoL) in Participants With Relapsed and/or Refractory Multiple Myeloma (RRMM) With Triple Class Exposure
NCT05217082 ·Status: COMPLETED