S0212 Celecoxib in Treating Patients With High-Grade Squamous Intraepithelial Lesions of the Cervix
NCT00072540 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-11-08
Summary
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. Celecoxib may be effective in preventing cervical cancer.
PURPOSE: Randomized phase II trial to study the effectiveness of celecoxib in preventing cervical cancer in patients who have high-grade squamous intraepithelial lesions of the cervix.
Conditions
- Stage 0 Cervical Cancer
- High-grade Squamous Intraepithelial Lesion
Interventions
- DRUG
-
celecoxib
- PROCEDURE
-
anti-cytokine therapy
- PROCEDURE
-
antiangiogenesis therapy
- PROCEDURE
-
biological therapy
- PROCEDURE
-
cancer prevention intervention
- PROCEDURE
-
chemoprevention of cancer
- PROCEDURE
-
enzyme inhibitor therapy
- PROCEDURE
-
growth factor antagonist therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
SWOG Cancer Research Network
lead NETWORK
Principal Investigators
-
William R. Robinson, MD · Harrington Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
More Related Trials
-
Celecoxib in Treating Patients With Head and Neck Cancer That Can Be Removed By Surgery
NCT00357617 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3
NCT00278434 ·Status: TERMINATED ·Phase: PHASE1
-
SU5416 in Treating Patients With Persistent or Recurrent Cervical Cancer
NCT00026260 ·Status: COMPLETED ·Phase: PHASE2
-
Molecular Effects of Short-Term Celecoxib Treatment on Head and Neck Squamous Cell Carcinoma
NCT00596219 ·Status: COMPLETED ·Phase: NA
-
Celecoxib as Adjuvant Biologic Therapy in Patients With Head and Neck and Lung Cancer
NCT00527982 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine in Treating Patients With Persistent or Recurrent Cancer of the Cervix
NCT00006224 ·Status: TERMINATED ·Phase: PHASE2
-
Study of SOR007 Ointment for Cervical Intraepithelial Neoplasia (CIN)
NCT03143491 ·Status: WITHDRAWN ·Phase: PHASE2
-
Capecitabine in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer
NCT00016926 ·Status: COMPLETED ·Phase: PHASE2
-
Liposomal Doxorubicin in Treating Patients With Persistent or Recurrent Cancer of the Cervix
NCT00030472 ·Status: TERMINATED ·Phase: PHASE2
-
Surgery With or Without Chemotherapy in Treating Patients With Stage IB Cervical Cancer
NCT00002536 ·Status: COMPLETED ·Phase: PHASE3
-
Capecitabine in Treating Patients With Persistent or Recurrent Cervical Cancer
NCT00039442 ·Status: COMPLETED ·Phase: PHASE2
-
A Trial to Evaluate the Efficacy and Safety of BLS-ILB-E710c in Patients With Cervical Intraepithelial Neoplasia 2/3 (CIN2/3)
NCT03274206 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia
NCT01925378 ·Status: WITHDRAWN ·Phase: PHASE2
-
Cetuximab and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer
NCT00101192 ·Status: COMPLETED ·Phase: PHASE2
-
SYS6002 vs Chemotherapy in Recurrent or Metastatic Cervical Cancer
NCT07230626 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Oxaliplatin in Treating Patients With Recurrent or Refractory Cervical Cancer
NCT00005837 ·Status: COMPLETED ·Phase: PHASE2
-
Gefitinib in Treating Patients With Cervical Cancer
NCT00049556 ·Status: COMPLETED ·Phase: PHASE2
-
Study of ZG005 in Combination With Gecacitinib in Participants With Advanced Cervical Cancer
NCT07080216 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase Ⅱ Study of F520 in Patients With Cervical Carcinoma
NCT06226350 ·Status: COMPLETED ·Phase: PHASE2
-
Cabozantinib Plus Pembrolizumab for Recurrent, Persistent and/or Metastatic Cervical Cancer
NCT04230954 ·Status: TERMINATED ·Phase: PHASE2
-
Vaccine Therapy in Treating Patients With Persistent or Recurrent Cervical Cancer
NCT01266460 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation Glizigen® and Ocoxin®-Viusid® in High-grade Cervical Intraepithelial Lesions
NCT03549273 ·Status: RECRUITING ·Phase: PHASE2
-
S9717 Tirapazamine Plus Cisplatin in Treating Patients With Metastatic, Recurrent, or Refractory Cervical Cancer
NCT00003369 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab Based Immunotherapy for Treatment of High Grade Cervical Dysplasia
NCT03808168 ·Status: WITHDRAWN ·Phase: PHASE2
-
Radiation Therapy and Chemotherapy in Treating Patients With Locally Advanced Cervical Cancer
NCT00054444 ·Status: COMPLETED ·Phase: PHASE1