Treatment of Multiple Sclerosis Using Over the Counter Inosine
NCT00067327 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2006-03-17
Summary
The purpose of this study is to determine whether raising low levels of the natural antioxidant uric acid by the administration of a precursor, inosine, has any therapeutic effect on the progression of Relapsing Remitting Multiple Sclerosis (RRMS) and secondary progressive Multiple Sclerosis (MS).
Conditions
- Multiple Sclerosis, Relapsing-Remitting
Interventions
- DRUG
-
Inosine
Sponsors & Collaborators
-
National Center for Complementary and Integrative Health (NCCIH)
lead NIH
Principal Investigators
-
Douglas C Hooper, PhD · Thomas Jefferson University
-
Hilary Koprowski, MD · Department of Microbiology and Immunology, Thomas Jefferson University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-02-28
- Completion
- 2005-09-30
Countries
- United States
Study Locations
More Related Trials
-
Neural Stem Cell Transplantation in Multiple Sclerosis Patients
NCT03269071 ·Status: COMPLETED ·Phase: PHASE1
-
An Intravenous Infusion Study of rHIgM22 in Patients With Multiple Sclerosis Immediately Following a Relapse
NCT02398461 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety and Efficacy Study of CNTO1275 in Patients With Multiple Sclerosis
NCT00207727 ·Status: COMPLETED ·Phase: PHASE2
-
Oral Guanabenz for Multiple Sclerosis
NCT02423083 ·Status: TERMINATED ·Phase: PHASE1
-
Ginseng in Treatment of Fatigue in Multiple Sclerosis
NCT01712373 ·Status: COMPLETED ·Phase: PHASE2
-
Allogenic Adipose Tissue-derived Mesenchymal Stromal Cells for the Treatment of Primary Progressive Multiple Sclerosis
NCT06592703 ·Status: RECRUITING ·Phase: PHASE1
-
Study Evaluating CCI-779 in Relapsing Multiple Sclerosis
NCT00228397 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety, Tolerability and Efficacy of AIN457 in Patients With Relapsing-remitting Multiple Sclerosis
NCT01433250 ·Status: COMPLETED ·Phase: PHASE2
-
Safety of RG2077 in Patients With Multiple Sclerosis
NCT00076934 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Yishen Daluo Yin Granule for Relapsing-Remitting Multiple Sclerosis
NCT07029867 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Melatonin in Relapsing-Remitting Multiple Sclerosis Patients
NCT01279876 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety, Tolerability, and Exploratory Efficacy of IMS001 in Subjects With Multiple Sclerosis
NCT04956744 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Study to Evaluate the Safety and Efficacy of PIPE-307 in Subjects With Relapsing-Remitting Multiple Sclerosis
NCT06083753 ·Status: COMPLETED ·Phase: PHASE2
-
EARLY IFNB-1a and Simvastatin Combination Therapy in Clinically Isolated Syndrome Suggestive of Multiple Sclerosis
NCT00146068 ·Status: COMPLETED ·Phase: PHASE4
-
Senolytics for Secondary Progressive MS
NCT07270120 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Improving the Treatment of Acute Relapses in Multiple Sclerosis Through Intranasal Methylprednisolone Administration
NCT06223074 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Stem Cells in Rapidly Evolving Active Multiple Sclerosis
NCT01606215 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Aspirin as a Pre-Treatment for Exercise in Multiple Sclerosis
NCT03051646 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Post-Authorization Safety Study of Interferon Beta Therapy in Participants With Multiple Sclerosis
NCT03347370 ·Status: COMPLETED
-
POC-MD MRI-based Trial in Relapsing-remitting Multiple Scler
NCT01051817 ·Status: COMPLETED ·Phase: PHASE2
-
Aspirin for Treatment of Multiple Sclerosis-Related Fatigue
NCT00467584 ·Status: TERMINATED ·Phase: PHASE3
-
Cranberry for Prevention of Urinary Tract Infections in Multiple Sclerosis Patients
NCT00280592 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)
NCT02637856 ·Status: COMPLETED ·Phase: PHASE3
-
Repeat Infusion of Autologous Bone Marrow Cells in Multiple Sclerosis
NCT01932593 ·Status: COMPLETED ·Phase: NA
-
Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis
NCT00848939 ·Status: COMPLETED ·Phase: PHASE1