Topical Imiquimod Compared With Surgery in Treating Patients With Basal Cell Skin Cancer
NCT00066872 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 500
Last updated 2013-09-17
Summary
RATIONALE: Biological therapies such as imiquimod use different ways to stimulate the immune system and stop cancer cells from growing. It is not yet known if topical imiquimod is more effective than surgery in treating basal cell skin cancer.
PURPOSE: This randomized phase III trial is studying how well topical imiquimod works compared to surgery in treating patients with basal cell skin cancer.
Conditions
- Non-melanomatous Skin Cancer
Interventions
- DRUG
-
imiquimod
- PROCEDURE
-
conventional surgery
Sponsors & Collaborators
-
Queen's Medical Center
lead OTHER
Principal Investigators
-
Mara Ozolins, MS · Queen's Medical Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-10-31
- Completion
- 2010-04-30
Countries
- United Kingdom
Study Locations
More Related Trials
-
Basal Cell Carcinoma Chemoprevention Trial
NCT05212246 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Treatment of Nodular Basal Cell Carcinoma (BCC) With Imiquimod 5% Cream After Curettage
NCT00314756 ·Status: COMPLETED ·Phase: PHASE4
-
Investigating the Effect of Topical Imiquimod on Sebaceous Hyperplasia
NCT06840470 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Safety and Efficacy of Imiquimod Applied in Dose-Cycle for Actinic Keratoses
NCT00175643 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety Trial of Topical Resiquimod Gel (0.06%) in Patients With Nodular Basal Cell Carcinoma
NCT01808950 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1
NCT00865644 ·Status: COMPLETED ·Phase: PHASE1
-
Imiquimod 5% Cream for the Treatment of Periocular Basal Cell Carcinoma
NCT00803907 ·Status: UNKNOWN ·Phase: PHASE4
-
Topical Imiquimod in Conjunction With Nd:YAG Laser for Tattoo Removal
NCT00638651 ·Status: COMPLETED ·Phase: PHASE1
-
Topical Imiquimod Cream in Combination With Cryotherapy for the Treatment of Actinic Keratoses
NCT00774787 ·Status: COMPLETED ·Phase: PHASE4
-
Topical Imiquimod in Treating Patients With Recurrent Paget's Disease of the Vulva
NCT00504023 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of Imiquimod Topical Cream in Early Stage Cutaneous T-cell Lymphoma
NCT02301494 ·Status: WITHDRAWN ·Phase: NA
-
Comparing Immune Responses to Topical Imiquimod
NCT04809662 ·Status: TERMINATED
-
Topical Vitamin C for Treatment of Basal Cell Cancer
NCT04279535 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Topical Ascorbic Acid for Treatment of Squamous Cell Skin Cancer
NCT05932511 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Efficacy and Safety of a New Topical Formulation With Imiquimod (Limtop) Applied 1, 3 or 7 Times Weekly During 2 x 2 Weeks Treatment for Actinic Keratosis on the Head
NCT01611480 ·Status: COMPLETED ·Phase: PHASE2
-
Topical Imiquimod Treatment of Oral Dysplasia
NCT07210775 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Topical Challenge With Omiganan and Imiquimod in Healthy Volunteers
NCT03071679 ·Status: COMPLETED ·Phase: PHASE1
-
Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions
NCT03233412 ·Status: COMPLETED ·Phase: PHASE2
-
Follow-up Study to Evaluate Sustained Clearance Rates of Actinic Keratoses up to One Year
NCT00668733 ·Status: COMPLETED
-
A Double-blind, Randomized, Single Centre, Vehicle-controlled Study to Evaluate the Safety and Tolerability of a New Topical Formulation Containing 0,09% Imiquimod (Limtop) in Healthy Subjects
NCT01567683 ·Status: COMPLETED ·Phase: PHASE1
-
Vismodegib for Treatment of Basal Cell Carcinoma
NCT01543581 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Therapy of Imiquimod 5%Cream and Cryotherapy vs Monotherapy for Common Warts:Randomized Comparative Trial.
NCT06973473 ·Status: NOT_YET_RECRUITING
-
Topical Resiquimod for the Treatment of Early Stage Cutaneous T Cell Lymphoma (CTCL)
NCT01676831 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Topical Imiquimod Versus Conization to Treat Cervical Intraepithelial Neoplasia
NCT01283763 ·Status: TERMINATED ·Phase: PHASE3
-
1-Year Follow up to the 1473-IMIQ Study
NCT00114023 ·Status: COMPLETED